Role of the Endocannabinoid System in the Central Regulation of Nonmammalian Vertebrate Reproduction

The endocannabinoid system (ECS) has a well-documented pivotal role in the control of mammalian reproductive functions, by acting at multiple levels, that is, central (CNS) and local (gonads) levels. Since studies performed in animal models other than mammals might provide further insight into the b...

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Main Authors: Erika Cottone, Valentina Pomatto, Patrizia Bovolin
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:International Journal of Endocrinology
Online Access:http://dx.doi.org/10.1155/2013/941237
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author Erika Cottone
Valentina Pomatto
Patrizia Bovolin
author_facet Erika Cottone
Valentina Pomatto
Patrizia Bovolin
author_sort Erika Cottone
collection DOAJ
description The endocannabinoid system (ECS) has a well-documented pivotal role in the control of mammalian reproductive functions, by acting at multiple levels, that is, central (CNS) and local (gonads) levels. Since studies performed in animal models other than mammals might provide further insight into the biology of these signalling molecules, in the present paper we review the comparative data pointing toward the endocannabinoid involvement in the reproductive control of non-mammalian vertebrates, focussing in particular on the central regulation of teleost and amphibian reproduction. The morphofunctional distribution of brain cannabinoid receptors will be discussed in relation to other crucial signalling molecules involved in the control of reproductive functions, such as GnRH, dopamine, aromatase, and pituitary gonadotropins.
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institution Kabale University
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series International Journal of Endocrinology
spelling doaj-art-fcd25989c72945f1a076b74f6d4e60342025-02-03T01:27:45ZengWileyInternational Journal of Endocrinology1687-83371687-83452013-01-01201310.1155/2013/941237941237Role of the Endocannabinoid System in the Central Regulation of Nonmammalian Vertebrate ReproductionErika Cottone0Valentina Pomatto1Patrizia Bovolin2Department of Life Science and Systems Biology, University of Turin, Via Accademia Albertina 13, 10123 Torino, ItalyDepartment of Life Science and Systems Biology, University of Turin, Via Accademia Albertina 13, 10123 Torino, ItalyDepartment of Life Science and Systems Biology, University of Turin, Via Accademia Albertina 13, 10123 Torino, ItalyThe endocannabinoid system (ECS) has a well-documented pivotal role in the control of mammalian reproductive functions, by acting at multiple levels, that is, central (CNS) and local (gonads) levels. Since studies performed in animal models other than mammals might provide further insight into the biology of these signalling molecules, in the present paper we review the comparative data pointing toward the endocannabinoid involvement in the reproductive control of non-mammalian vertebrates, focussing in particular on the central regulation of teleost and amphibian reproduction. The morphofunctional distribution of brain cannabinoid receptors will be discussed in relation to other crucial signalling molecules involved in the control of reproductive functions, such as GnRH, dopamine, aromatase, and pituitary gonadotropins.http://dx.doi.org/10.1155/2013/941237
spellingShingle Erika Cottone
Valentina Pomatto
Patrizia Bovolin
Role of the Endocannabinoid System in the Central Regulation of Nonmammalian Vertebrate Reproduction
International Journal of Endocrinology
title Role of the Endocannabinoid System in the Central Regulation of Nonmammalian Vertebrate Reproduction
title_full Role of the Endocannabinoid System in the Central Regulation of Nonmammalian Vertebrate Reproduction
title_fullStr Role of the Endocannabinoid System in the Central Regulation of Nonmammalian Vertebrate Reproduction
title_full_unstemmed Role of the Endocannabinoid System in the Central Regulation of Nonmammalian Vertebrate Reproduction
title_short Role of the Endocannabinoid System in the Central Regulation of Nonmammalian Vertebrate Reproduction
title_sort role of the endocannabinoid system in the central regulation of nonmammalian vertebrate reproduction
url http://dx.doi.org/10.1155/2013/941237
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