Role of the Endocannabinoid System in the Central Regulation of Nonmammalian Vertebrate Reproduction
The endocannabinoid system (ECS) has a well-documented pivotal role in the control of mammalian reproductive functions, by acting at multiple levels, that is, central (CNS) and local (gonads) levels. Since studies performed in animal models other than mammals might provide further insight into the b...
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Format: | Article |
Language: | English |
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Wiley
2013-01-01
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Series: | International Journal of Endocrinology |
Online Access: | http://dx.doi.org/10.1155/2013/941237 |
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author | Erika Cottone Valentina Pomatto Patrizia Bovolin |
author_facet | Erika Cottone Valentina Pomatto Patrizia Bovolin |
author_sort | Erika Cottone |
collection | DOAJ |
description | The endocannabinoid system (ECS) has a well-documented pivotal role in the control of mammalian reproductive functions, by acting at multiple levels, that is, central (CNS) and local (gonads) levels. Since studies performed in animal models other than mammals might provide further insight into the biology of these signalling molecules, in the present paper we review the comparative data pointing toward the endocannabinoid involvement in the reproductive control of non-mammalian vertebrates, focussing in particular on the central regulation of teleost and amphibian reproduction. The morphofunctional distribution of brain cannabinoid receptors will be discussed in relation to other crucial signalling molecules involved in the control of reproductive functions, such as GnRH, dopamine, aromatase, and pituitary gonadotropins. |
format | Article |
id | doaj-art-fcd25989c72945f1a076b74f6d4e6034 |
institution | Kabale University |
issn | 1687-8337 1687-8345 |
language | English |
publishDate | 2013-01-01 |
publisher | Wiley |
record_format | Article |
series | International Journal of Endocrinology |
spelling | doaj-art-fcd25989c72945f1a076b74f6d4e60342025-02-03T01:27:45ZengWileyInternational Journal of Endocrinology1687-83371687-83452013-01-01201310.1155/2013/941237941237Role of the Endocannabinoid System in the Central Regulation of Nonmammalian Vertebrate ReproductionErika Cottone0Valentina Pomatto1Patrizia Bovolin2Department of Life Science and Systems Biology, University of Turin, Via Accademia Albertina 13, 10123 Torino, ItalyDepartment of Life Science and Systems Biology, University of Turin, Via Accademia Albertina 13, 10123 Torino, ItalyDepartment of Life Science and Systems Biology, University of Turin, Via Accademia Albertina 13, 10123 Torino, ItalyThe endocannabinoid system (ECS) has a well-documented pivotal role in the control of mammalian reproductive functions, by acting at multiple levels, that is, central (CNS) and local (gonads) levels. Since studies performed in animal models other than mammals might provide further insight into the biology of these signalling molecules, in the present paper we review the comparative data pointing toward the endocannabinoid involvement in the reproductive control of non-mammalian vertebrates, focussing in particular on the central regulation of teleost and amphibian reproduction. The morphofunctional distribution of brain cannabinoid receptors will be discussed in relation to other crucial signalling molecules involved in the control of reproductive functions, such as GnRH, dopamine, aromatase, and pituitary gonadotropins.http://dx.doi.org/10.1155/2013/941237 |
spellingShingle | Erika Cottone Valentina Pomatto Patrizia Bovolin Role of the Endocannabinoid System in the Central Regulation of Nonmammalian Vertebrate Reproduction International Journal of Endocrinology |
title | Role of the Endocannabinoid System in the Central Regulation of Nonmammalian Vertebrate Reproduction |
title_full | Role of the Endocannabinoid System in the Central Regulation of Nonmammalian Vertebrate Reproduction |
title_fullStr | Role of the Endocannabinoid System in the Central Regulation of Nonmammalian Vertebrate Reproduction |
title_full_unstemmed | Role of the Endocannabinoid System in the Central Regulation of Nonmammalian Vertebrate Reproduction |
title_short | Role of the Endocannabinoid System in the Central Regulation of Nonmammalian Vertebrate Reproduction |
title_sort | role of the endocannabinoid system in the central regulation of nonmammalian vertebrate reproduction |
url | http://dx.doi.org/10.1155/2013/941237 |
work_keys_str_mv | AT erikacottone roleoftheendocannabinoidsysteminthecentralregulationofnonmammalianvertebratereproduction AT valentinapomatto roleoftheendocannabinoidsysteminthecentralregulationofnonmammalianvertebratereproduction AT patriziabovolin roleoftheendocannabinoidsysteminthecentralregulationofnonmammalianvertebratereproduction |