Cell‐Specific Transposable Element and Gene Expression Analysis Across Systemic Lupus Erythematosus Phenotypes

Objective There is an established yet unexplained link between interferon (IFN) and systemic lupus erythematosus (SLE). The expression of sequences derived from transposable elements (TEs) may contribute to SLE phenotypes, specifically production of type I IFNs and generation of autoantibodies. Meth...

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Main Authors: Zachary Cutts, Sarah Patterson, Lenka Maliskova, Kimberly E. Taylor, Chun Jimmie Ye, Maria Dall'Era, Jinoos Yazdany, Lindsey A. Criswell, Gabriela K. Fragiadakis, Charles Langelier, John A. Capra, Marina Sirota, Cristina M. Lanata
Format: Article
Language:English
Published: Wiley 2024-11-01
Series:ACR Open Rheumatology
Online Access:https://doi.org/10.1002/acr2.11713
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