The Role of Dual Mutations G347E and E349D of the Pigeon Paramyxovirus Type 1 Hemagglutinin–Neuraminidase Protein In Vitro and In Vivo

The Role of Dual Mutations G347E and E349D of the Pigeon Paramyxovirus Type 1 Hemagglutinin–Neuraminidase Protein In Vitro and In Vivo

Pigeon Newcastle disease (ND) is the most common viral infectious disease in the pigeon industry, caused by pigeon paramyxovirus type 1 (PPMV-1), a variant of chicken-origin Newcastle disease virus (NDV). Previous studies have identified significant amino acid differences between PPMV-1 and chicken-...

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Bibliographic Details
Main Authors: Yu Chen, Junhao Gong, Tiansong Zhan, Mingzhan Wang, Shunlin Hu, Xiufan Liu
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Veterinary Sciences
Subjects:
pigeon ND
PPMV-1
HN protein
pathogenicity
cross-species transmission
antigenic variation
Online Access:https://www.mdpi.com/2306-7381/11/12/592
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