RETRACTED ARTICLE: hERG1 channels modulate integrin signaling to trigger angiogenesis and tumor progression in colorectal cancer
Abstract Angiogenesis is a potential target for cancer therapy. We identified a novel signaling pathway that sustains angiogenesis and progression in colorectal cancer (CRC). This pathway is triggered by β1 integrin-mediated adhesion and leads to VEGF-A secretion. The effect is modulated by the huma...
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Main Authors: | , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2013-11-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/srep03308 |
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