Oxypeucedanin hydrate alleviates rheumatoid arthritis by inhibiting the TLR4-MD2/NF-κB/MAPK signaling axis

Oxypeucedanin hydrate alleviates rheumatoid arthritis by inhibiting the TLR4-MD2/NF-κB/MAPK signaling axis

Rheumatoid arthritis (RA) is an idiopathic and chronic autoimmune disease for which there are currently no effective treatments. Oxypeucedanin hydrate (OXH) is a natural coumarin known for its potent anti-inflammatory properties. However, f...

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Bibliographic Details
Main Authors: Liu Mengdan, Huo Xueyan, Li Congcong, Hu Yunjie, Lei Haoran, Wang Dong, Zhu Lin, Gu Yucheng, Guo Dale, Huang Lijun, Deng Yun
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2024-05-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
oxypeucedanin hydrate
rheumatoid arthritis
TLR4-MD2 complex
NF-κB/MAPK pathway
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2024076
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https://www.sciengine.com/doi/10.3724/abbs.2024076

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