Extracellular vesicle mimetics as delivery vehicles for oligonucleotide-based therapeutics and plasmid DNA

Extracellular vesicle mimetics as delivery vehicles for oligonucleotide-based therapeutics and plasmid DNA

IntroductionSmall membrane particles called extracellular vesicles (EVs) transport biologically active cargo between cells, providing intercellular communication. The clinical application of EVs is limited due to the lack of scalable and cost-effective approaches for their production and purificatio...

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Main Authors: Anastasiya Oshchepkova, Ivan Chernikov, Svetlana Miroshnichenko, Olga Patutina, Oleg Markov, Innokenty Savin, Yaroslav Staroseletz, Mariya Meschaninova, Pavel Puchkov, Sergey Zhukov, Maxim Kupryushkin, Mikhail Maslov, Aleksandra Sen’kova, Valentin Vlassov, Elena Chernolovskaya, Marina Zenkova
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-10-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
extracellular vesicle mimetics
cytochalasin B
multidrug resistance
melanoma
siRNA
antisense oligonucleotide (ASO)
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2024.1437817/full
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https://www.frontiersin.org/articles/10.3389/fbioe.2024.1437817/full

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