Mitochondrial pathways of copper neurotoxicity: focus on mitochondrial dynamics and mitophagy

Copper (Cu) is essential for brain development and function, yet its overload induces neuronal damage and contributes to neurodegeneration and other neurological disorders. Multiple studies demonstrated that Cu neurotoxicity is associated with mitochondrial dysfunction, routinely assessed by reducti...

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Main Authors: Michael Aschner, Anatoly V. Skalny, Rongzhu Lu, Airton C. Martins, Yousef Tizabi, Sergey V. Nekhoroshev, Abel Santamaria, Anton I. Sinitskiy, Alexey A. Tinkov
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Molecular Neuroscience
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Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2024.1504802/full
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