Psychobiotics, Novel Therapeutic Agents for the Psychiatric Disorders
Various neurological disorders such as Parkinson’s disease, Alzheimer’s disease, autism spectrum disorder in young children, stress, anxiety etc., are afflicting the people all over the world. The pathophysiology of some of these disorders is not fully understood. Furthermore, the conventional the...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
The National Information and Documentation Centre (NIDOC) , Egypt
2025-02-01
|
| Series: | Novel Research in Microbiology Journal |
| Subjects: | |
| Online Access: | https://researcherslinks.com/current-issues/Psychobiotics-Novel-Therapeutic-Agents/44/8/10553/html |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832095438286618624 |
|---|---|
| author | Praveen Reddy P. K. Sandhya Aparna Srikantam |
| author_facet | Praveen Reddy P. K. Sandhya Aparna Srikantam |
| author_sort | Praveen Reddy P. |
| collection | DOAJ |
| description | Various neurological disorders such as Parkinson’s disease, Alzheimer’s disease, autism spectrum
disorder in young children, stress, anxiety etc., are afflicting the people all over the world. The pathophysiology
of some of these disorders is not fully understood. Furthermore, the conventional therapies are not effective
for all patients with psychiatric disorders. Hence, alternative therapeutic strategies/agents are much needed.
Clinical researchers suggest that certain microorganisms (beneficial microorganisms/probiotics) could be
substituted for conventional therapies and/ or can be used in combination with current drugs. Such beneficial
microorganisms which can influence the central nervous system and cure the neurological complications are
referred to as psychobiotics. In fact, the psychobiotics are the probiotic/ prebiotic agents which when present
in the human gut region will not only improve the gut health but also influence the central nervous system via
gut-brain axis, and counteract the symptoms of various neurological disorders. Till date, numerous probiotic
bacteria and prebiotic compounds were identified and the majority of them are able to influence the nervous
system. In various clinical trials on animal models and humans, it was proved that psychobiotics are effective
in ameliorating the clinical symptoms of neurological disorders. Some of the researchers are employing
psychobiotics in combination with traditional drugs for treatment of the psychiatric disorders. The aim of the
current review is to investigate the concept of psychobiotics, detailing their mechanisms of action and discussing
their potential applications in the treatment of certain psychiatric disorders. Subsequently, this study delineated
the characteristics of psychobiotics and highlighted their impacts on the nervous system. Additionally, various
psychobiotics utilized in the management of specific psychiatric conditions have been examined based on
numerous clinical trials and experiments conducted on both animal models and human subjects. |
| format | Article |
| id | doaj-art-fbb15cf907a945c6911135ece7a16aee |
| institution | Kabale University |
| issn | 2537-0286 2537-0294 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | The National Information and Documentation Centre (NIDOC) , Egypt |
| record_format | Article |
| series | Novel Research in Microbiology Journal |
| spelling | doaj-art-fbb15cf907a945c6911135ece7a16aee2025-02-05T18:48:31ZengThe National Information and Documentation Centre (NIDOC) , EgyptNovel Research in Microbiology Journal2537-02862537-02942025-02-01912840https://dx.doi.org/10.17582/journal.NRMJ/2025/9.1.28.40Psychobiotics, Novel Therapeutic Agents for the Psychiatric DisordersPraveen Reddy P. 0K. Sandhya1Aparna Srikantam2Department of Microbiology, School of Allied and Healthcare Sciences, Malla Reddy University, Maisammaguda, Dulapally, Hyderabad-500100, Telangana, IndiaDepartment of Microbiology, School of Allied and Healthcare Sciences, Malla Reddy University, Maisammaguda, Dulapally, Hyderabad-500100, Telangana, IndiaDepartment of Microbiology, School of Allied and Healthcare Sciences, Malla Reddy University, Maisammaguda, Dulapally, Hyderabad-500100, Telangana, IndiaVarious neurological disorders such as Parkinson’s disease, Alzheimer’s disease, autism spectrum disorder in young children, stress, anxiety etc., are afflicting the people all over the world. The pathophysiology of some of these disorders is not fully understood. Furthermore, the conventional therapies are not effective for all patients with psychiatric disorders. Hence, alternative therapeutic strategies/agents are much needed. Clinical researchers suggest that certain microorganisms (beneficial microorganisms/probiotics) could be substituted for conventional therapies and/ or can be used in combination with current drugs. Such beneficial microorganisms which can influence the central nervous system and cure the neurological complications are referred to as psychobiotics. In fact, the psychobiotics are the probiotic/ prebiotic agents which when present in the human gut region will not only improve the gut health but also influence the central nervous system via gut-brain axis, and counteract the symptoms of various neurological disorders. Till date, numerous probiotic bacteria and prebiotic compounds were identified and the majority of them are able to influence the nervous system. In various clinical trials on animal models and humans, it was proved that psychobiotics are effective in ameliorating the clinical symptoms of neurological disorders. Some of the researchers are employing psychobiotics in combination with traditional drugs for treatment of the psychiatric disorders. The aim of the current review is to investigate the concept of psychobiotics, detailing their mechanisms of action and discussing their potential applications in the treatment of certain psychiatric disorders. Subsequently, this study delineated the characteristics of psychobiotics and highlighted their impacts on the nervous system. Additionally, various psychobiotics utilized in the management of specific psychiatric conditions have been examined based on numerous clinical trials and experiments conducted on both animal models and human subjects.https://researcherslinks.com/current-issues/Psychobiotics-Novel-Therapeutic-Agents/44/8/10553/htmlneurological disorderspsychobioticsprobiotics/prebioticsgut-brain axisclinical trials |
| spellingShingle | Praveen Reddy P. K. Sandhya Aparna Srikantam Psychobiotics, Novel Therapeutic Agents for the Psychiatric Disorders Novel Research in Microbiology Journal neurological disorders psychobiotics probiotics/prebiotics gut-brain axis clinical trials |
| title | Psychobiotics, Novel Therapeutic Agents for the Psychiatric Disorders |
| title_full | Psychobiotics, Novel Therapeutic Agents for the Psychiatric Disorders |
| title_fullStr | Psychobiotics, Novel Therapeutic Agents for the Psychiatric Disorders |
| title_full_unstemmed | Psychobiotics, Novel Therapeutic Agents for the Psychiatric Disorders |
| title_short | Psychobiotics, Novel Therapeutic Agents for the Psychiatric Disorders |
| title_sort | psychobiotics novel therapeutic agents for the psychiatric disorders |
| topic | neurological disorders psychobiotics probiotics/prebiotics gut-brain axis clinical trials |
| url | https://researcherslinks.com/current-issues/Psychobiotics-Novel-Therapeutic-Agents/44/8/10553/html |
| work_keys_str_mv | AT praveenreddyp psychobioticsnoveltherapeuticagentsforthepsychiatricdisorders AT ksandhya psychobioticsnoveltherapeuticagentsforthepsychiatricdisorders AT aparnasrikantam psychobioticsnoveltherapeuticagentsforthepsychiatricdisorders |