Structured observations reveal slow HIV-1 CTL escape.

Structured observations reveal slow HIV-1 CTL escape.

The existence of viral variants that escape from the selection pressures imposed by cytotoxic T-lymphocytes (CTLs) in HIV-1 infection is well documented, but it is unclear when they arise, with reported measures of the time to escape in individuals ranging from days to years. A study of participants...

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Main Authors: Hannah E Roberts, Jacob Hurst, Nicola Robinson, Helen Brown, Peter Flanagan, Laura Vass, Sarah Fidler, Jonathan Weber, Abdel Babiker, Rodney E Phillips, Angela R McLean, John Frater, SPARTAC trial investigators
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-02-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1004914
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https://doi.org/10.1371/journal.pgen.1004914

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