Extrapolating evidence for molecularly targeted therapies from common to rare cancers: a scoping review of methodological guidance
Objectives Cancer is increasingly classified according to biomarkers that drive tumour growth and therapies developed to target them. In rare biomarker-defined cancers, randomised controlled trials to adequately assess targeted therapies may be infeasible. Extrapolating existing evidence of targeted...
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Main Authors: | Sarah J Lord, Saskia Cheyne, John Simes, Doah Cho, Chee Khoon Lee |
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Format: | Article |
Language: | English |
Published: |
BMJ Publishing Group
2022-07-01
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Series: | BMJ Open |
Online Access: | https://bmjopen.bmj.com/content/12/7/e058350.full |
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