Extrapolating evidence for molecularly targeted therapies from common to rare cancers: a scoping review of methodological guidance

Objectives Cancer is increasingly classified according to biomarkers that drive tumour growth and therapies developed to target them. In rare biomarker-defined cancers, randomised controlled trials to adequately assess targeted therapies may be infeasible. Extrapolating existing evidence of targeted...

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Bibliographic Details
Main Authors: Sarah J Lord, Saskia Cheyne, John Simes, Doah Cho, Chee Khoon Lee
Format: Article
Language:English
Published: BMJ Publishing Group 2022-07-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/12/7/e058350.full
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