Higher skeletal muscle mitochondrial oxidative capacity is associated with preserved brain structure up to over a decade

Abstract Impaired muscle mitochondrial oxidative capacity is associated with future cognitive impairment, and higher levels of PET and blood biomarkers of Alzheimer’s disease and neurodegeneration. Here, we examine its associations with up to over a decade-long changes in brain atrophy and microstru...

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Bibliographic Details
Main Authors: Qu Tian, Erin E. Greig, Christos Davatzikos, Bennett A. Landman, Susan M. Resnick, Luigi Ferrucci
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-55009-z
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