Simultaneous determination of warfarin and 7-hydroxywarfarin in rat plasma by HPLC-FLD
In this study, high-performance liquid chromatography with fluorescence detection (HPLC-FLD) has been used for the first time, for direct determination of warfarin and its major metabolite, 7-hydroxywarfarin, in rat plasma. The simple and sensitive method was developed using Fortis® reversed-phase d...
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Main Authors: | Zayed Aref, Babaresh Wahby M., Darweesh Ruba S., El-Elimat Tamam |
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Format: | Article |
Language: | English |
Published: |
Sciendo
2020-09-01
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Series: | Acta Pharmaceutica |
Subjects: | |
Online Access: | https://doi.org/10.2478/acph-2020-0025 |
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