Simultaneous determination of warfarin and 7-hydroxywarfarin in rat plasma by HPLC-FLD

In this study, high-performance liquid chromatography with fluorescence detection (HPLC-FLD) has been used for the first time, for direct determination of warfarin and its major metabolite, 7-hydroxywarfarin, in rat plasma. The simple and sensitive method was developed using Fortis® reversed-phase d...

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Bibliographic Details
Main Authors: Zayed Aref, Babaresh Wahby M., Darweesh Ruba S., El-Elimat Tamam
Format: Article
Language:English
Published: Sciendo 2020-09-01
Series:Acta Pharmaceutica
Subjects:
Online Access:https://doi.org/10.2478/acph-2020-0025
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