Intensified conditioning containing decitabine versus standard myeloablative conditioning for adult patients with KMT2A-rearranged leukemia: a multicenter retrospective study

Intensified conditioning containing decitabine versus standard myeloablative conditioning for adult patients with KMT2A-rearranged leukemia: a multicenter retrospective study

Abstract Background Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is recommended for patients with KMT2A-rearranged (KMT2A-r) leukemia whereas relapse remains high. We aimed to determine whether intensified conditioning containing decitabine (Dec) could reduce relapse compared with...

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Main Authors: Zhongli Hu, Zinan Feng, Shiqi Liu, Hai He, Ying Dong, Zhiping Fan, Yiqing Li, Fen Huang, Na Xu, Can Liu, Yunxin Zeng, Ping Zhu, Ren Lin, Hua Jin, Xiong Zhang, Ruijuan Sun, Qifa Liu, Li Xuan
Format: Article
Language:English
Published: BMC 2024-12-01
Series:BMC Medicine
Subjects:
Decitabine
Intensified conditioning
Allo-HSCT
KMT2A-r leukemia
Online Access:https://doi.org/10.1186/s12916-024-03830-0
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https://doi.org/10.1186/s12916-024-03830-0

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