Rational selection of TbpB variants yields a bivalent vaccine with broad coverage against Neisseria gonorrhoeae

Abstract Neisseria gonorrhoeae is an on-going public health problem due in part to the lack of success with efforts to develop an efficacious vaccine to prevent this sexually transmitted infection. The gonococcal transferrin binding protein B (TbpB) is an attractive candidate vaccine antigen. Howeve...

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Bibliographic Details
Main Authors: Jamie E. Fegan, Epshita A. Islam, David M. Curran, Dixon Ng, Natalie Y. T. Au, Elissa G. Currie, Joseph J. Zeppa, Jessica Lam, Anthony B. Schryvers, Trevor F. Moraes, Scott D. Gray-Owen
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-024-01054-0
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