Unraveling the genetic landscape of high-risk retinoblastoma through transcriptome profiling

Unraveling the genetic landscape of high-risk retinoblastoma through transcriptome profiling

Retinoblastoma (RB), a rare and aggressive pediatric cancer, presents severe challenges in treatment due to its genetic complexity. It's crucial to develop tailored therapies for high-risk RB cases. We conducted transcriptome profiling to investigate gene expression patterns and identify geneti...

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Bibliographic Details
Main Authors: Mukesh Kumar, Vikas Shrivastava, Isha Goel, Manoj Phalak, Sanjay kumar Mishra, Pramod Kumar Sharma, Amit Katiyar, Tej P. Singh, Punit Kaur
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Chemical Physics Impact
Subjects:
Retinoblastoma
RNA-seq
Transcriptome profile
Biomarkers
Therapeutic targets
Molecular docking
Online Access:http://www.sciencedirect.com/science/article/pii/S2667022425000234
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