Pathogenesis-directed therapy of methylphenidate-induced oxidative heart damage in rats

Pathogenesis-directed therapy of methylphenidate-induced oxidative heart damage in rats

AimThe current study aimed to investigate the protective effects of adenosine triphosphate (ATP), metyrosine, and melatonin on possible methylphenidate cardiotoxicity in rats using biochemical and histopathological methods.MethodsThirty rats were separated into five groups: healthy (HG), methylpheni...

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Bibliographic Details
Main Authors: Izzet Emir, Seval Bulut, Bahadır Suleyman, Renad Mammadov, Nurinisa Yucel, Betul Cicek, Gulce Naz Yazici, Durdu Altuner, Murat Gunay, Halis Suleyman
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Pharmacology
Subjects:
adenosine triphosphate
melatonin
methylphenidate
metyrosine
oxidative stress
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1503032/full
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https://www.frontiersin.org/articles/10.3389/fphar.2024.1503032/full

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