Burkitt's Lymphoma in a Pregnant Woman: Case Report and Review of the Literature
Burkitt's lymphoma (BL) is an aggressive B-cell malignancy with very high proliferation rate, more common in males than females. Here, we describe a case of Burkitt's lymphoma in a 24-week pregnant woman with cervical and abdominal involvement. The common genetic event of virtually all BL...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Case Reports in Oncological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2013/370179 |
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| author | Carlos Zagalo Francesca Pierdomenico José Cabeçadas Pedro David Santos |
| author_facet | Carlos Zagalo Francesca Pierdomenico José Cabeçadas Pedro David Santos |
| author_sort | Carlos Zagalo |
| collection | DOAJ |
| description | Burkitt's lymphoma (BL) is an aggressive B-cell malignancy with very high proliferation rate, more common in males than females. Here, we describe a case of Burkitt's lymphoma in a 24-week pregnant woman with cervical and abdominal involvement. The common genetic event of virtually all BL is a reciprocal chromosomal translocation involving the proto-oncogene MYC and one of the Ig gene heavy or light chain loci. Supportive treatment was administered until early delivery, after which the patient was treated according to protocol LMB96. Pregnancy and tumorogenesis share some important events such as immunologic tolerance, angiogenesis, and editing the host immune response. Little is known about the relationship between these events in pregnancy and in tumorogenesis. |
| format | Article |
| id | doaj-art-fa9383ecd2d44641a9a218e7af77b1b8 |
| institution | Kabale University |
| issn | 2090-6706 2090-6714 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Oncological Medicine |
| spelling | doaj-art-fa9383ecd2d44641a9a218e7af77b1b82025-02-03T01:02:13ZengWileyCase Reports in Oncological Medicine2090-67062090-67142013-01-01201310.1155/2013/370179370179Burkitt's Lymphoma in a Pregnant Woman: Case Report and Review of the LiteratureCarlos Zagalo0Francesca Pierdomenico1José Cabeçadas2Pedro David Santos3Egas Moniz, Health Sciences Institute, Quinta da Granja, Monte de Caparica, 2829-511 Caparica, PortugalServiço de Hematologia, Instituto Português de Oncologia de Lisboa Francisco Gentil EPE, Rua Professor Lima Basto, 1099-023 Lisboa, PortugalServiço de Anatomia Patológica, Instituto Português de Oncologia de Lisboa Francisco Gentil EPE, Rua Professor Lima Basto, 1099-023 Lisboa, PortugalInstituto Ciências Biomédicas Abel Salazar, Universidade do Porto, Rua de Jorge Viterbo Ferreira No. 228, 4050-313 Porto, PortugalBurkitt's lymphoma (BL) is an aggressive B-cell malignancy with very high proliferation rate, more common in males than females. Here, we describe a case of Burkitt's lymphoma in a 24-week pregnant woman with cervical and abdominal involvement. The common genetic event of virtually all BL is a reciprocal chromosomal translocation involving the proto-oncogene MYC and one of the Ig gene heavy or light chain loci. Supportive treatment was administered until early delivery, after which the patient was treated according to protocol LMB96. Pregnancy and tumorogenesis share some important events such as immunologic tolerance, angiogenesis, and editing the host immune response. Little is known about the relationship between these events in pregnancy and in tumorogenesis.http://dx.doi.org/10.1155/2013/370179 |
| spellingShingle | Carlos Zagalo Francesca Pierdomenico José Cabeçadas Pedro David Santos Burkitt's Lymphoma in a Pregnant Woman: Case Report and Review of the Literature Case Reports in Oncological Medicine |
| title | Burkitt's Lymphoma in a Pregnant Woman: Case Report and Review of the Literature |
| title_full | Burkitt's Lymphoma in a Pregnant Woman: Case Report and Review of the Literature |
| title_fullStr | Burkitt's Lymphoma in a Pregnant Woman: Case Report and Review of the Literature |
| title_full_unstemmed | Burkitt's Lymphoma in a Pregnant Woman: Case Report and Review of the Literature |
| title_short | Burkitt's Lymphoma in a Pregnant Woman: Case Report and Review of the Literature |
| title_sort | burkitt s lymphoma in a pregnant woman case report and review of the literature |
| url | http://dx.doi.org/10.1155/2013/370179 |
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