Impact of fatigue in Crohn's disease is negatively related to resting state functional connectivity between the superior parietal lobule and parahippocampal gyrus/hippocampus

Impact of fatigue in Crohn's disease is negatively related to resting state functional connectivity between the superior parietal lobule and parahippocampal gyrus/hippocampus

IntroductionCrohn's disease is one phenotype of inflammatory bowel disease (IBD). Fatigue is a common and burdensome symptom for persons with Crohn's disease. Despite its detrimental impact on health-related quality of life, the pathophysiology of fatigue in Crohn's disease is not ful...

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Bibliographic Details
Main Authors: Theresa A. McIver, Charles N. Bernstein, Ruth Ann Marrie, Chase R. Figley, Md Nasir Uddin, John D. Fisk, Lesley A. Graff, Ronak Patel, Erin L. Mazerolle, Jennifer Kornelsen
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Human Neuroscience
Subjects:
Crohn's disease
functional connectivity
disease activity
fatigue
fMRI
Online Access:https://www.frontiersin.org/articles/10.3389/fnhum.2025.1561421/full
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https://www.frontiersin.org/articles/10.3389/fnhum.2025.1561421/full

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