Study on the protective effect of mitochonic acid-5 on septic acute kidney injury and the underlying mechanism
目的探讨线粒体酸5（mitochonic acid-5，MA-5）是否可以减轻脂多糖（lipopolysaccharide，LPS）诱导的脓毒症急性肾损伤以及可能的机制。方法细胞实验：将肾小管细胞分为正常组、MA-5（10 µmol/L）组、LPS（10 mg/L）刺激组和LPS+MA-5治疗组，通过细胞计数试剂盒8法评估细胞活力、流式细胞术评估细胞凋亡率；活性氧（reactive oxygen species，ROS）检测试剂盒检测ROS含量；三磷酸腺苷（adenosine triphosphate，ATP）检测试剂盒检测ATP水平；蛋白质印迹法（western blot，Wb）检测沉默信息...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | zho |
| Published: |
Editorial Department of Journal of Clinical Nephrology
2025-01-01
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| Series: | Linchuang shenzangbing zazhi |
| Subjects: | |
| Online Access: | http://www.lcszb.com/article/doi/10.3969/j.issn.1671-2390.2025.01.009 |
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