IFN-γ/TNF-α Synergism Induces Pro-Inflammatory Cytokine and Chemokine Production by In Vitro Canine Keratinocytes

IFN-γ/TNF-α Synergism Induces Pro-Inflammatory Cytokine and Chemokine Production by In Vitro Canine Keratinocytes

Activated keratinocytes play a crucial role in skin inflammation through the production of multiple inflammatory mediators; however, little is known about cytokine secretion by activated keratinocytes in dogs. This study aimed to investigate the effects of the Th1 and Th2 types of cytokines on the p...

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Bibliographic Details
Main Authors: Kyungsook Jung, Ji-Yeong Ku, Je-Seong Kwon, Gayeon Won, Hakyoung Yoon, Sang-Ik Oh, Mi Hye Kim, Chongchan Kim, Ji-Seon Yoon
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Veterinary Sciences
Subjects:
canine
keratinocyte
interferon γ
tumor necrosis factor α
synergistic effects
pro-inflammatory cytokine
Online Access:https://www.mdpi.com/2306-7381/12/1/55
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