Transcriptome and DNA methylation profiling during the NSN to SN transition in mouse oocytes

Abstract Background During the latter stages of their development, mammalian oocytes under dramatic chromatin reconfiguration, transitioning from a non-surrounded nucleolus (NSN) to a surrounded nucleolus (SN) stage, and concomitant transcriptional silencing. Although the NSN-SN transition is known...

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Bibliographic Details
Main Authors: Hannah Demond, Soumen Khan, Juan Castillo-Fernandez, Courtney W. Hanna, Gavin Kelsey
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Molecular and Cell Biology
Subjects:
Online Access:https://doi.org/10.1186/s12860-024-00527-3
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