VapC toxins promote the pathogenesis of Rickettsia heilongjiangensis by cleaving essential RNAs from both Rickettsia and its host.
Toxin-antitoxin (TA) modules enable bacteria to persist under stressful environments. However, they are typically absent from host-associated prokaryotes due to their potential host toxicity. Here, the obligate intracellular bacterium spotted fever group (SFG) rickettsiae, which causes mild to sever...
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| Main Authors: | Yan Liu, Weiting Zhou, Jiaying Zhao, Qingyin Shi, Yu Xin, Xuan Ouyang, Yonghui Yu, Jun Jiao, Maozhang He, Yajun Song, Kehan Xu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2025-07-01
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| Series: | PLoS Pathogens |
| Online Access: | https://doi.org/10.1371/journal.ppat.1013380 |
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