Characterization of breast cancer tumors in older patients who show de novo resistance to endocrine therapy

Characterization of breast cancer tumors in older patients who show de novo resistance to endocrine therapy

Abstract The standard treatment for hormone receptor-positive breast cancer in good general condition is curative surgery followed by endocrine therapy. However, for older patients, endocrine therapy alone is sometimes chosen instead of curative surgery due to health conditions or personal preferenc...

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Main Authors: Yumiko Ishizuka, Yoshiya Horimoto, Men Yuan, Yuko Ueki, Hiroko Onagi, Harumi Saeki, Takuo Hayashi, Tsuyoshi Saito, Takahiko Kawate, Takashi Ishikawa, Hidetaka Eguchi, Junichiro Watanabe, Goro Kutomi
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
Subjects:
Breast cancer
Endocrine therapy
De novo resistance
Older patients
Personalized medicine
Online Access:https://doi.org/10.1038/s41598-024-83895-2
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https://doi.org/10.1038/s41598-024-83895-2

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