Inhibition of Immune Complex-Induced Inflammation by A small Molecular Weight Selectin Antagonist

The anti-inflammatory effect of a small molecular weight antagonist of P- and E-selectin-dependent cell adhesion was examined. The glycolipid sulphatide was shown to block the adherence of thrombin-activated rat platelets to HL-60 cells. This interaction is known to be dependent on P-selectin. The r...

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Bibliographic Details
Main Authors: X. Nair, G. Todderud, L. Davern, D. Lee, A. Aruffo, K. M. Tramposch
Format: Article
Language:English
Published: Wiley 1994-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/S0962935194000657
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