Acute Truncal Lymphedema Secondary to Axillary Metastatic Melanoma Presenting Like Cellulitis
There are reported cases of diphencyprone used in treating cutaneous metastases of melanoma. Here, we report a patient with previous primary melanoma on his left back treated with surgical excision and lymphadenectomy, followed by radiotherapy for the recurrent tumor on the primary site. Despite rad...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2017-01-01
|
| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2017/5462929 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832556859679047680 |
|---|---|
| author | Shelley J. E. Hwang Benjamin Y. Kong Shaun Chou Deepal Wakade Matteo S. Carlino Pablo Fernandez-Penas |
| author_facet | Shelley J. E. Hwang Benjamin Y. Kong Shaun Chou Deepal Wakade Matteo S. Carlino Pablo Fernandez-Penas |
| author_sort | Shelley J. E. Hwang |
| collection | DOAJ |
| description | There are reported cases of diphencyprone used in treating cutaneous metastases of melanoma. Here, we report a patient with previous primary melanoma on his left back treated with surgical excision and lymphadenectomy, followed by radiotherapy for the recurrent tumor on the primary site. Despite radiotherapy and treatment with dabrafenib and trametinib, in-transit metastases have developed and topical diphencyprone was applied to these metastases. Six weeks later, the patient developed fever and a spreading erythematous tender indurated plaque covering the left side of the body including axillae, back, and flank, clinically suggestive of cellulitis. Systemic antibiotic therapy did not improve the condition and a biopsy showed sparse lymphocytic infiltrate. With the diagnosis of possible acute lymphedema, a CT scan was requested that showed significant axillary lymph node metastasis. The fever was considered secondary to dabrafenib and trametinib therapy. This case highlights that, in patients with lymphadenectomy, atypical forms of lymphedema on the body may appear. Truncal lymphedema is an infrequent event. |
| format | Article |
| id | doaj-art-f98d184b71c246b39efb74e0ba84bbd8 |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-f98d184b71c246b39efb74e0ba84bbd82025-02-03T05:44:14ZengWileyCase Reports in Medicine1687-96271687-96352017-01-01201710.1155/2017/54629295462929Acute Truncal Lymphedema Secondary to Axillary Metastatic Melanoma Presenting Like CellulitisShelley J. E. Hwang0Benjamin Y. Kong1Shaun Chou2Deepal Wakade3Matteo S. Carlino4Pablo Fernandez-Penas5Department of Dermatology, Westmead Hospital, Westmead, NSW, AustraliaCrown Princess Mary Cancer Centre, Westmead Hospital, Westmead, NSW, AustraliaDepartment of Tissue Pathology, Westmead Hospital, Westmead, NSW, AustraliaDepartment of Dermatology, Westmead Hospital, Westmead, NSW, AustraliaSydney Medical School, The University of Sydney, Sydney, NSW, AustraliaDepartment of Dermatology, Westmead Hospital, Westmead, NSW, AustraliaThere are reported cases of diphencyprone used in treating cutaneous metastases of melanoma. Here, we report a patient with previous primary melanoma on his left back treated with surgical excision and lymphadenectomy, followed by radiotherapy for the recurrent tumor on the primary site. Despite radiotherapy and treatment with dabrafenib and trametinib, in-transit metastases have developed and topical diphencyprone was applied to these metastases. Six weeks later, the patient developed fever and a spreading erythematous tender indurated plaque covering the left side of the body including axillae, back, and flank, clinically suggestive of cellulitis. Systemic antibiotic therapy did not improve the condition and a biopsy showed sparse lymphocytic infiltrate. With the diagnosis of possible acute lymphedema, a CT scan was requested that showed significant axillary lymph node metastasis. The fever was considered secondary to dabrafenib and trametinib therapy. This case highlights that, in patients with lymphadenectomy, atypical forms of lymphedema on the body may appear. Truncal lymphedema is an infrequent event.http://dx.doi.org/10.1155/2017/5462929 |
| spellingShingle | Shelley J. E. Hwang Benjamin Y. Kong Shaun Chou Deepal Wakade Matteo S. Carlino Pablo Fernandez-Penas Acute Truncal Lymphedema Secondary to Axillary Metastatic Melanoma Presenting Like Cellulitis Case Reports in Medicine |
| title | Acute Truncal Lymphedema Secondary to Axillary Metastatic Melanoma Presenting Like Cellulitis |
| title_full | Acute Truncal Lymphedema Secondary to Axillary Metastatic Melanoma Presenting Like Cellulitis |
| title_fullStr | Acute Truncal Lymphedema Secondary to Axillary Metastatic Melanoma Presenting Like Cellulitis |
| title_full_unstemmed | Acute Truncal Lymphedema Secondary to Axillary Metastatic Melanoma Presenting Like Cellulitis |
| title_short | Acute Truncal Lymphedema Secondary to Axillary Metastatic Melanoma Presenting Like Cellulitis |
| title_sort | acute truncal lymphedema secondary to axillary metastatic melanoma presenting like cellulitis |
| url | http://dx.doi.org/10.1155/2017/5462929 |
| work_keys_str_mv | AT shelleyjehwang acutetruncallymphedemasecondarytoaxillarymetastaticmelanomapresentinglikecellulitis AT benjaminykong acutetruncallymphedemasecondarytoaxillarymetastaticmelanomapresentinglikecellulitis AT shaunchou acutetruncallymphedemasecondarytoaxillarymetastaticmelanomapresentinglikecellulitis AT deepalwakade acutetruncallymphedemasecondarytoaxillarymetastaticmelanomapresentinglikecellulitis AT matteoscarlino acutetruncallymphedemasecondarytoaxillarymetastaticmelanomapresentinglikecellulitis AT pablofernandezpenas acutetruncallymphedemasecondarytoaxillarymetastaticmelanomapresentinglikecellulitis |