Elevated levels of aquaporin-4-containing extracellular vesicles in cerebrospinal fluid of patients with bipolar disorder

Elevated levels of aquaporin-4-containing extracellular vesicles in cerebrospinal fluid of patients with bipolar disorder

Objectives: To examine a hypothetical dysfunction of the brain water channels in bipolar disorder by analyzing aquaporin-4 (AQP4) exposing extracellular vesicles (EVs) in cerebrospinal fluid (CSF) from individuals with bipolar disorder types 1 and 2, and healthy controls. Methods: We analyzed exposu...

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Bibliographic Details
Main Authors: Lennart Wetterberg, Fariborz Mobarrez, Rolf Nybom, Håkan Wallén, Aurimantas Pelanis, Dietrich von Rosen, Mikael Landén
Format: Article
Language:English
Published: Upsala Medical Society 2025-03-01
Series:Upsala Journal of Medical Sciences
Subjects:
aquaporin-4
extracellular vesicles
cerebrospinal fluid
flow cytometry
Online Access:https://ujms.net/index.php/ujms/article/view/12006/19309
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https://ujms.net/index.php/ujms/article/view/12006/19309

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