𝛽-Thalassemia: HiJAKing Ineffective Erythropoiesis and Iron Overload
𝛽-thalassemia encompasses a group of monogenic diseases that have in common defective synthesis of 𝛽-globin. The defects involved are extremely heterogeneous and give rise to a large phenotypic spectrum, with patients that are almost asymptomatic to cases in which regular blood transfusions are requ...
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Main Authors: | Luca Melchiori, Sara Gardenghi, Stefano Rivella |
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Format: | Article |
Language: | English |
Published: |
Wiley
2010-01-01
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Series: | Advances in Hematology |
Online Access: | http://dx.doi.org/10.1155/2010/938640 |
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