Biosynthesis of Lysosomally Escaped Apoptotic Bodies Inhibits Inflammasome Synthesis in Macrophages
Hyperglycemia and bacterial colonization in diabetic wounds aberrantly activate Nod-like receptor protein 3 (NLRP3) in macrophages, resulting in extensive inflammatory infiltration and impaired wound healing. Targeted suppression of the NLRP3 inflammasome shows promise in reducing macrophage inflamm...
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Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
American Association for the Advancement of Science (AAAS)
2025-01-01
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Series: | Research |
Online Access: | https://spj.science.org/doi/10.34133/research.0581 |
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