Liposomal Formulation of Hydroxychloroquine Can Inhibit Autophagy In Vivo

Liposomal Formulation of Hydroxychloroquine Can Inhibit Autophagy In Vivo

<b>Background/Objectives:</b> Preclinical studies have shown that the anti-malarial drug hydroxychloroquine (HCQ) improves the anti-cancer effects of various therapeutic agents by impairing autophagy. These findings are difficult to translate in vivo as reaching an effective HCQ concentr...

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Bibliographic Details
Main Authors: Wieslawa H. Dragowska, Jagbir Singh, Mohamed Wehbe, Malathi Anantha, Katarina Edwards, Sharon M. Gorski, Marcel B. Bally, Ada W. Y. Leung
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Pharmaceutics
Subjects:
liposomes
hydroxychloroquine
autophagy
breast cancer
gefitinib
Online Access:https://www.mdpi.com/1999-4923/17/1/42
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