Risperidone-Induced Neutropenia in a Schizophrenic Patient: A Case Report and Literature Review

Neutropenia is an adverse effect of various pharmacological therapies, including antipsychotics. Among the second-generation antipsychotic (SGA) medications, clozapine is most notable for neutropenic adverse effect. Risperidone, another SGA drug, is linked mainly with metabolic adverse effects, but...

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Main Authors: Ayodele Atolagbe, Stanley Nkemjika, Olusegun Popoola, Oluwatoyin Oladeji, Irina Kogan, Haroon Saeed, Tolulope Olupona
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Case Reports in Psychiatry
Online Access:http://dx.doi.org/10.1155/2021/3980872
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author Ayodele Atolagbe
Stanley Nkemjika
Olusegun Popoola
Oluwatoyin Oladeji
Irina Kogan
Haroon Saeed
Tolulope Olupona
author_facet Ayodele Atolagbe
Stanley Nkemjika
Olusegun Popoola
Oluwatoyin Oladeji
Irina Kogan
Haroon Saeed
Tolulope Olupona
author_sort Ayodele Atolagbe
collection DOAJ
description Neutropenia is an adverse effect of various pharmacological therapies, including antipsychotics. Among the second-generation antipsychotic (SGA) medications, clozapine is most notable for neutropenic adverse effect. Risperidone, another SGA drug, is linked mainly with metabolic adverse effects, but rarely, blood dyscrasia adverse reactions have been reported. Hence, we report the case of a 56-year-old African American woman who developed severe neutropenia following two weeks of oral risperidone treatment. Her neutrophil levels returned to normal limits following discontinuation of risperidone and switching to haloperidol.
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institution Kabale University
issn 2090-682X
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language English
publishDate 2021-01-01
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series Case Reports in Psychiatry
spelling doaj-art-f8e70ccd410844c3be45c7e9cc8e4bfd2025-02-03T01:27:06ZengWileyCase Reports in Psychiatry2090-682X2090-68382021-01-01202110.1155/2021/39808723980872Risperidone-Induced Neutropenia in a Schizophrenic Patient: A Case Report and Literature ReviewAyodele Atolagbe0Stanley Nkemjika1Olusegun Popoola2Oluwatoyin Oladeji3Irina Kogan4Haroon Saeed5Tolulope Olupona6Department of Psychiatry, Interfaith Medical Center, Brooklyn, NYC, NY, USADepartment of Psychiatry, Interfaith Medical Center, Brooklyn, NYC, NY, USADepartment of Psychiatry, Interfaith Medical Center, Brooklyn, NYC, NY, USADepartment of Psychiatry, Interfaith Medical Center, Brooklyn, NYC, NY, USADepartment of Psychiatry, Interfaith Medical Center, Brooklyn, NYC, NY, USADepartment of Psychiatry, Interfaith Medical Center, Brooklyn, NYC, NY, USADepartment of Psychiatry, Interfaith Medical Center, Brooklyn, NYC, NY, USANeutropenia is an adverse effect of various pharmacological therapies, including antipsychotics. Among the second-generation antipsychotic (SGA) medications, clozapine is most notable for neutropenic adverse effect. Risperidone, another SGA drug, is linked mainly with metabolic adverse effects, but rarely, blood dyscrasia adverse reactions have been reported. Hence, we report the case of a 56-year-old African American woman who developed severe neutropenia following two weeks of oral risperidone treatment. Her neutrophil levels returned to normal limits following discontinuation of risperidone and switching to haloperidol.http://dx.doi.org/10.1155/2021/3980872
spellingShingle Ayodele Atolagbe
Stanley Nkemjika
Olusegun Popoola
Oluwatoyin Oladeji
Irina Kogan
Haroon Saeed
Tolulope Olupona
Risperidone-Induced Neutropenia in a Schizophrenic Patient: A Case Report and Literature Review
Case Reports in Psychiatry
title Risperidone-Induced Neutropenia in a Schizophrenic Patient: A Case Report and Literature Review
title_full Risperidone-Induced Neutropenia in a Schizophrenic Patient: A Case Report and Literature Review
title_fullStr Risperidone-Induced Neutropenia in a Schizophrenic Patient: A Case Report and Literature Review
title_full_unstemmed Risperidone-Induced Neutropenia in a Schizophrenic Patient: A Case Report and Literature Review
title_short Risperidone-Induced Neutropenia in a Schizophrenic Patient: A Case Report and Literature Review
title_sort risperidone induced neutropenia in a schizophrenic patient a case report and literature review
url http://dx.doi.org/10.1155/2021/3980872
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