Allelic frequency of 12-FGF4RG and the association between the genotype with number of calcified intervertebral discs visible on radiographs in Coton de Tuléar and French Bulldog breeds

Allelic frequency of 12-FGF4RG and the association between the genotype with number of calcified intervertebral discs visible on radiographs in Coton de Tuléar and French Bulldog breeds

Abstract Background Intervertebral disc disease (IVDD) is a major welfare issue in chondrodystrophic dogs. It is a consequence of chondroid metaplasia of the nucleus pulposus, leading to premature degeneration and calcification of the intervertebral discs (IVDs). Radiographic grading based on the nu...

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Bibliographic Details
Main Authors: Vilma L. J. Reunanen, Tarja S. Jokinen, Liisa Lilja-Maula, Marjo K. Hytönen, Anu K. Lappalainen
Format: Article
Language:English
Published: BMC 2025-03-01
Series:BMC Veterinary Research
Subjects:
FGF4 retrogene1
Allele2
Dog3
Intervertebral disc disease4
Imaging5
Spine6
Online Access:https://doi.org/10.1186/s12917-025-04573-7
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https://doi.org/10.1186/s12917-025-04573-7

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