Validation of Hv1 channel functions in BV2 microglial cells using small molecule modulators

Microglia are the first responders to insults or damages in the brain where they display both beneficial and detrimental effects. Excessively activated microglia aggravate the secondary damage by producing several proinflammatory mediators. Voltage-gated proton channels, Hv1 are selectively expresse...

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Bibliographic Details
Main Authors: Ashutosh Sharma, Nandini B. Kale, Priyanka Yadav, Shivani Yadav, Madhavi Ranawat, Valmik S. Shinde, Aravind Singh Kshatri
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Cellular Neuroscience
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Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2025.1624224/full
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