Postendodontic Pain after Pulpotomy or Root Canal Treatment in Mature Teeth with Carious Pulp Exposure: A Multicenter Randomized Controlled Trial
This equivalence, randomized, clinical trial aimed to compare the postoperative pain of root canal therapy (RCT) with pulpotomy with mineral trioxide aggregate (PMTA) or calcium-enriched mixture (PCEM) in permanent mature teeth. In seven academic centers, 550 cariously exposed pulps were included an...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Pain Research and Management |
| Online Access: | http://dx.doi.org/10.1155/2020/5853412 |
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| author | Mohammad Jafar Eghbal Ali Haeri Arash Shahravan Ali Kazemi Fariborz Moazami Mohammad Ali Mozayeni Eshaghali Saberi Mohammad Samiei Mehdi Vatanpour Alireza Akbarzade Baghban Mahta Fazlyab Ardavan Parhizkar Mahboobe Ahmadi Nazila Akbarian Rad Shima Bijari Delaram Bineshmarvasti Paria Davoudi Roya Dehghan Mandana Dehghani Habibollah Ebrahimi Nafiseh Emami Nafiseh Farajian Rahim Fereidooni Gelareh Ghobadi Mostafa Ghodrati Atefeh Gohari Azadeh Hashemi Mohammadreza Hosseini Elham Karami Nasir Kheirabadi Sepideh Kozegari Hadi Labaf Ghasemi Alireza Majidi Parastu Malekzadeh Vahid Mehrabi Mehrnush Mohammadi Leila Moradi Eslami Atefeh Noghani Negin Omatali Negar Pourhatami Behnam Rahbani Nobar Saeid Rahmani Parviz Shafaq Sara Soofiabadi Somaye Teimoori Farzaneh Vatandoost Saeed Asgary |
| author_facet | Mohammad Jafar Eghbal Ali Haeri Arash Shahravan Ali Kazemi Fariborz Moazami Mohammad Ali Mozayeni Eshaghali Saberi Mohammad Samiei Mehdi Vatanpour Alireza Akbarzade Baghban Mahta Fazlyab Ardavan Parhizkar Mahboobe Ahmadi Nazila Akbarian Rad Shima Bijari Delaram Bineshmarvasti Paria Davoudi Roya Dehghan Mandana Dehghani Habibollah Ebrahimi Nafiseh Emami Nafiseh Farajian Rahim Fereidooni Gelareh Ghobadi Mostafa Ghodrati Atefeh Gohari Azadeh Hashemi Mohammadreza Hosseini Elham Karami Nasir Kheirabadi Sepideh Kozegari Hadi Labaf Ghasemi Alireza Majidi Parastu Malekzadeh Vahid Mehrabi Mehrnush Mohammadi Leila Moradi Eslami Atefeh Noghani Negin Omatali Negar Pourhatami Behnam Rahbani Nobar Saeid Rahmani Parviz Shafaq Sara Soofiabadi Somaye Teimoori Farzaneh Vatandoost Saeed Asgary |
| author_sort | Mohammad Jafar Eghbal |
| collection | DOAJ |
| description | This equivalence, randomized, clinical trial aimed to compare the postoperative pain of root canal therapy (RCT) with pulpotomy with mineral trioxide aggregate (PMTA) or calcium-enriched mixture (PCEM) in permanent mature teeth. In seven academic centers, 550 cariously exposed pulps were included and randomly allocated into PMTA (n = 188), PCEM (n = 194), or RCT (n = 168) arms. Preoperative “Pain Intensity” (PI) on Numerical Rating Scale and postoperative PIs until day 7 were recorded. Patients’ demographic and pre-/intra-/postoperative factors/conditions were recorded/analysed. The arms were homogeneous in terms of demographics. The mean preoperative PIs were similar (P=0.998), the mean sum PIs recorded during 10 postoperative intervals were comparable (P=0.939), and the trend/changes in pain relief were parallel (P=0.821) in all study arms. The incidences of preoperative moderate-severe pain in RCT, PMTA, and PCEM arms were 56.5%, 55.7%, and 56.7%, which after 24 hours considerably decreased to 13.1%, 10.6%, and 12.9%, respectively (P=0.578). The time span of endodontic procedures was statistically different; RCT = 69.73, PMTA = 35.37, and PCEM = 33.62 minutes (P<0.001). Patients with greater preoperative pain, symptomatic apical periodontitis, or presence of PDL widening suffered more pain (P=0.002, 0.035, and 0.023, resp.); however, other pre-/intra-/postoperative factors/conditions were comparable. Pulpotomy with MTA/CEM and RCT demonstrate comparable and effective postoperative pain relief. |
| format | Article |
| id | doaj-art-f8ad8c1a3d3d450d90faf32e444249b2 |
| institution | Kabale University |
| issn | 1203-6765 1918-1523 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Pain Research and Management |
| spelling | doaj-art-f8ad8c1a3d3d450d90faf32e444249b22025-02-03T01:05:22ZengWileyPain Research and Management1203-67651918-15232020-01-01202010.1155/2020/58534125853412Postendodontic Pain after Pulpotomy or Root Canal Treatment in Mature Teeth with Carious Pulp Exposure: A Multicenter Randomized Controlled TrialMohammad Jafar Eghbal0Ali Haeri1Arash Shahravan2Ali Kazemi3Fariborz Moazami4Mohammad Ali Mozayeni5Eshaghali Saberi6Mohammad Samiei7Mehdi Vatanpour8Alireza Akbarzade Baghban9Mahta Fazlyab10Ardavan Parhizkar11Mahboobe Ahmadi12Nazila Akbarian Rad13Shima Bijari14Delaram Bineshmarvasti15Paria Davoudi16Roya Dehghan17Mandana Dehghani18Habibollah Ebrahimi19Nafiseh Emami20Nafiseh Farajian21Rahim Fereidooni22Gelareh Ghobadi23Mostafa Ghodrati24Atefeh Gohari25Azadeh Hashemi26Mohammadreza Hosseini27Elham Karami28Nasir Kheirabadi29Sepideh Kozegari30Hadi Labaf Ghasemi31Alireza Majidi32Parastu Malekzadeh33Vahid Mehrabi34Mehrnush Mohammadi35Leila Moradi Eslami36Atefeh Noghani37Negin Omatali38Negar Pourhatami39Behnam Rahbani Nobar40Saeid Rahmani41Parviz Shafaq42Sara Soofiabadi43Somaye Teimoori44Farzaneh Vatandoost45Saeed Asgary46Iranian Center for Endodontic Research, Research Institute for Dental Sciences, Shahid Beheshti University of Medical Sciences, Tehran 1983963113, IranIranian Center for Endodontic Research, Research Institute for Dental Sciences, Shahid Beheshti University of Medical Sciences, Tehran 1983963113, IranEndodontology Research Center, Endodontic Department, Dental School, Kerman University of Medical Sciences, Kerman 7618751689, IranEndodontic Department, Dental School, Shahed University, Tehran 1417755351, IranEndodontic Department, Dental School, Shiraz University of Medical Science, Shiraz 7134814336, IranEndodontic Department, Dental School, Shahid Beheshti University of Medical Sciences, Tehran 1983963113, IranEndodontic Department, Oral and Dental Diseases Research Center, Dental School, Zahedan University of Medical Sciences, Zahedan 9816743463, IranEndodontic Department, Dental School, Tabriz University of Medical Sciences, Tabriz 5166614713, IranEndodontic Department, Dental Branch, Islamic Azad University, Tehran 1946853314, IranDepartment of Basic Sciences, Proteomics Research Center, School of Rehabilitation, Shahid Beheshti University of Medical Sciences, Tehran 1616913111, IranEndodontic Department, Dental Branch, Islamic Azad University, Tehran 1946853314, IranIranian Center for Endodontic Research, Research Institute for Dental Sciences, Shahid Beheshti University of Medical Sciences, Tehran 1983963113, IranEndodontic Department, Oral and Dental Diseases Research Center, Dental School, Zahedan University of Medical Sciences, Zahedan 9816743463, IranEndodontic Department, Dental School, Shahid Beheshti University of Medical Sciences, Tehran 1983963113, IranEndodontic Department, Oral and Dental Diseases Research Center, Dental School, Zahedan University of Medical Sciences, Zahedan 9816743463, IranEndodontic Department, Dental Branch, Islamic Azad University, Tehran 1946853314, IranEndodontic Department, Dental School, Tabriz University of Medical Sciences, Tabriz 5166614713, IranEndodontic Department, Dental School, Shiraz University of Medical Science, Shiraz 7134814336, IranEndodontic Department, Dental School, Shiraz University of Medical Science, Shiraz 7134814336, IranEndodontic Department, Oral and Dental Diseases Research Center, Dental School, Zahedan University of Medical Sciences, Zahedan 9816743463, IranEndodontic Department, Dental Branch, Islamic Azad University, Tehran 1946853314, IranEndodontic Department, Dental School, Shahed University, Tehran 1417755351, IranEndodontology Research Center, Endodontic Department, Dental School, Kerman University of Medical Sciences, Kerman 7618751689, IranEndodontic Department, Dental Branch, Islamic Azad University, Tehran 1946853314, IranEndodontic Department, Dental School, Tabriz University of Medical Sciences, Tabriz 5166614713, IranEndodontic Department, Dental School, Shahid Beheshti University of Medical Sciences, Tehran 1983963113, IranEndodontology Research Center, Endodontic Department, Dental School, Kerman University of Medical Sciences, Kerman 7618751689, IranEndodontic Department, Dental School, Shahid Beheshti University of Medical Sciences, Tehran 1983963113, IranEndodontic Department, Dental School, Shiraz University of Medical Science, Shiraz 7134814336, IranEndodontology Research Center, Endodontic Department, Dental School, Kerman University of Medical Sciences, Kerman 7618751689, IranEndodontic Department, Dental School, Tabriz University of Medical Sciences, Tabriz 5166614713, IranEndodontic Department, Dental Branch, Islamic Azad University, Tehran 1946853314, IranEndodontic Department, Dental School, Tabriz University of Medical Sciences, Tabriz 5166614713, IranEndodontic Department, Dental School, Shiraz University of Medical Science, Shiraz 7134814336, IranEndodontic Department, Dental School, Shiraz University of Medical Science, Shiraz 7134814336, IranEndodontic Department, Dental School, Tabriz University of Medical Sciences, Tabriz 5166614713, IranEndodontic Department, Dental Branch, Islamic Azad University, Tehran 1946853314, IranEndodontic Department, Dental School, Tabriz University of Medical Sciences, Tabriz 5166614713, IranEndodontic Department, Dental Branch, Islamic Azad University, Tehran 1946853314, IranEndodontic Department, Dental School, Shiraz University of Medical Science, Shiraz 7134814336, IranEndodontic Department, Dental School, Shahid Beheshti University of Medical Sciences, Tehran 1983963113, IranEndodontology Research Center, Endodontic Department, Dental School, Kerman University of Medical Sciences, Kerman 7618751689, IranEndodontic Department, Dental School, Shahid Beheshti University of Medical Sciences, Tehran 1983963113, IranEndodontology Research Center, Endodontic Department, Dental School, Kerman University of Medical Sciences, Kerman 7618751689, IranEndodontic Department, Dental School, Shahed University, Tehran 1417755351, IranEndodontic Department, Dental School, Shahid Beheshti University of Medical Sciences, Tehran 1983963113, IranIranian Center for Endodontic Research, Research Institute for Dental Sciences, Shahid Beheshti University of Medical Sciences, Tehran 1983963113, IranThis equivalence, randomized, clinical trial aimed to compare the postoperative pain of root canal therapy (RCT) with pulpotomy with mineral trioxide aggregate (PMTA) or calcium-enriched mixture (PCEM) in permanent mature teeth. In seven academic centers, 550 cariously exposed pulps were included and randomly allocated into PMTA (n = 188), PCEM (n = 194), or RCT (n = 168) arms. Preoperative “Pain Intensity” (PI) on Numerical Rating Scale and postoperative PIs until day 7 were recorded. Patients’ demographic and pre-/intra-/postoperative factors/conditions were recorded/analysed. The arms were homogeneous in terms of demographics. The mean preoperative PIs were similar (P=0.998), the mean sum PIs recorded during 10 postoperative intervals were comparable (P=0.939), and the trend/changes in pain relief were parallel (P=0.821) in all study arms. The incidences of preoperative moderate-severe pain in RCT, PMTA, and PCEM arms were 56.5%, 55.7%, and 56.7%, which after 24 hours considerably decreased to 13.1%, 10.6%, and 12.9%, respectively (P=0.578). The time span of endodontic procedures was statistically different; RCT = 69.73, PMTA = 35.37, and PCEM = 33.62 minutes (P<0.001). Patients with greater preoperative pain, symptomatic apical periodontitis, or presence of PDL widening suffered more pain (P=0.002, 0.035, and 0.023, resp.); however, other pre-/intra-/postoperative factors/conditions were comparable. Pulpotomy with MTA/CEM and RCT demonstrate comparable and effective postoperative pain relief.http://dx.doi.org/10.1155/2020/5853412 |
| spellingShingle | Mohammad Jafar Eghbal Ali Haeri Arash Shahravan Ali Kazemi Fariborz Moazami Mohammad Ali Mozayeni Eshaghali Saberi Mohammad Samiei Mehdi Vatanpour Alireza Akbarzade Baghban Mahta Fazlyab Ardavan Parhizkar Mahboobe Ahmadi Nazila Akbarian Rad Shima Bijari Delaram Bineshmarvasti Paria Davoudi Roya Dehghan Mandana Dehghani Habibollah Ebrahimi Nafiseh Emami Nafiseh Farajian Rahim Fereidooni Gelareh Ghobadi Mostafa Ghodrati Atefeh Gohari Azadeh Hashemi Mohammadreza Hosseini Elham Karami Nasir Kheirabadi Sepideh Kozegari Hadi Labaf Ghasemi Alireza Majidi Parastu Malekzadeh Vahid Mehrabi Mehrnush Mohammadi Leila Moradi Eslami Atefeh Noghani Negin Omatali Negar Pourhatami Behnam Rahbani Nobar Saeid Rahmani Parviz Shafaq Sara Soofiabadi Somaye Teimoori Farzaneh Vatandoost Saeed Asgary Postendodontic Pain after Pulpotomy or Root Canal Treatment in Mature Teeth with Carious Pulp Exposure: A Multicenter Randomized Controlled Trial Pain Research and Management |
| title | Postendodontic Pain after Pulpotomy or Root Canal Treatment in Mature Teeth with Carious Pulp Exposure: A Multicenter Randomized Controlled Trial |
| title_full | Postendodontic Pain after Pulpotomy or Root Canal Treatment in Mature Teeth with Carious Pulp Exposure: A Multicenter Randomized Controlled Trial |
| title_fullStr | Postendodontic Pain after Pulpotomy or Root Canal Treatment in Mature Teeth with Carious Pulp Exposure: A Multicenter Randomized Controlled Trial |
| title_full_unstemmed | Postendodontic Pain after Pulpotomy or Root Canal Treatment in Mature Teeth with Carious Pulp Exposure: A Multicenter Randomized Controlled Trial |
| title_short | Postendodontic Pain after Pulpotomy or Root Canal Treatment in Mature Teeth with Carious Pulp Exposure: A Multicenter Randomized Controlled Trial |
| title_sort | postendodontic pain after pulpotomy or root canal treatment in mature teeth with carious pulp exposure a multicenter randomized controlled trial |
| url | http://dx.doi.org/10.1155/2020/5853412 |
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