Interleukin-6 “Trans-Signaling” and Ischemic Vascular Disease: The Important Role of Soluble gp130
Inflammation plays a major role in the onset of cardiovascular disease (CVD). Interleukine-6 (IL-6) is a multifunctional cytokine involved both in the beneficial acute inflammatory response and in the detrimental chronic low-grade systemic inflammation. Large genetic human studies, using Mendelian r...
Saved in:
Main Authors: | Mario Luca Morieri, Angelina Passaro, Giovanni Zuliani |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2017-01-01
|
Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1155/2017/1396398 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Role of soluble gp130 in the tumour necrosis factor-α expression and its production by peripheral blood mononuclear cells
by: E. Jablonskaca, et al.
Published: (2003-01-01) -
A GP130-Targeting Small Molecule, LMT-28, Reduces LPS-Induced Bone Resorption around Implants in Diabetic Models by Inhibiting IL-6/GP130/JAK2/STAT3 Signaling
by: Qi-qi Liu, et al.
Published: (2023-01-01) -
Multiple Myeloma and B Cell Lymphoma. Investigation of IL-6, IL-6 Receptor Antagonist (IL-6RA), and GP130 Antagonist (GP130A) Using Various Parameters in an In Vitro Model
by: Eva Kovacs
Published: (2006-01-01) -
The role of interleukin-6 classic and trans-signaling and interleukin-11 classic signaling in gastric cancer cells
by: Josephine Runge, et al.
Published: (2024-08-01) -
Role of interleukin-15 and interleukin-18 in the secretion of sIL-6R and sgp130 by human neutrophils
by: E. Jablonska, et al.
Published: (2003-01-01)