New Role for L-Arginine in Regulation of Inducible Nitric-Oxide-Synthase-Derived Superoxide Anion Production in Raw 264.7 Macrophages

Dietary supplementation with L-arginine was shown to improve immune responses in various inflammatory models. However, the molecular mechanisms underlying L-arginine effects on immune cells remain unrecognized. Herein, we tested the hypothesis that a limitation of L-arginine could lead to the uncoup...

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Bibliographic Details
Main Authors: Michaela Pekarova, Antonin Lojek, Hana Martiskova, Ondrej Vasicek, Lucia Bino, A. Klinke, D. Lau, Radek Kuchta, Jaroslav Kadlec, Radimir Vrba, Lukas Kubala
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/2011/321979
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