Pomolic acid induces ferroptosis-mediated cell death in non-small cell lung cancer

Pomolic acid induces ferroptosis-mediated cell death in non-small cell lung cancer

IntroductionPomolic acid (PA), a bioactive compound derived from Potentilla freyniana Bornm., is used palliatively for non-small cell lung cancer (NSCLC) in China’s Dongzu region, with some reports of clinical efficacy. However, the specific underlying molecular mechanisms remain unclear. This study...

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Bibliographic Details
Main Authors: Wenbin Ji, Yanbin Zhang, Wenhao Ji, Hui Zhang, Biao Qin, Xiao-Liang Xing, Zaiqi Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Pharmacology
Subjects:
PA
ferroptosis
NSCLC
network pharmacology
ferroptosis-related proteins
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1567942/full
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https://www.frontiersin.org/articles/10.3389/fphar.2025.1567942/full

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