Betatrophin Acts as a Diagnostic Biomarker in Type 2 Diabetes Mellitus and Is Negatively Associated with HDL-Cholesterol

Betatrophin Acts as a Diagnostic Biomarker in Type 2 Diabetes Mellitus and Is Negatively Associated with HDL-Cholesterol

Objective. By assessing its circulating concentrations in type 2 diabetes mellitus (T2DM) patients, we aimed to explore the associations of betatrophin with various metabolic parameters and evaluate its diagnostic value in T2DM. Methods. A total of 58 non-diabetes-mellitus (NDM) subjects and 73 age-...

Full description

Saved in:

Bibliographic Details
Main Authors:	Min Yi, Rong-ping Chen, Rui Yang, Xian-feng Guo, Jia-chun Zhang, Hong Chen
Format:	Article
Language:	English
Published:	Wiley 2015-01-01
Series:	International Journal of Endocrinology
Online Access:	http://dx.doi.org/10.1155/2015/479157
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

HDL-free cholesterol influx into macrophages and transfer to LDL correlate with HDL-free cholesterol content
by: Dedipya Yelamanchili, et al.
Published: (2025-01-01)

Synthesis and QSAR Study of Some HDL Cholesterol Increasing Quinazolinone Derivatives
by: M. B. Deshmukh, et al.
Published: (2004-01-01)

Dynamics of HDL-Cholesterol Following a Post-Myocardial Infarction Cardiac Rehabilitation Program
by: Carlos Bertolín-Boronat, et al.
Published: (2025-01-01)

Non-HDL cholesterol: A valid surrogate marker to apolipoprotein b100 in type 2 diabetes mellitus patients in assessment of risk of cardiovascular diseases
by: Vidyashree, et al.
Published: (2024-07-01)

Circulating Levels of Betatrophin and Irisin Are Not Associated with Pancreatic β-Cell Function in Previously Diagnosed Type 2 Diabetes Mellitus Patients
by: Lingshu Wang, et al.
Published: (2016-01-01)

Association between Serum Uric Acid to HDL-Cholesterol Ratio and Nonalcoholic Fatty Liver Disease in Lean Chinese Adults
by: Ya-Nan Zhang, et al.
Published: (2020-01-01)

Increased Circulating Betatrophin Concentrations in Patients with Type 2 Diabetes
by: Daniel Espes, et al.
Published: (2014-01-01)

Moderate-Intensity Exercise and Musical Co-Treatment Decreased the Circulating Level of Betatrophin
by: Hendra Susanto, et al.
Published: (2020-01-01)

Role of High-Density Lipoprotein Cholesterol (HDL-C) as a Clinical Predictor of Decompensation in Patients with Chronic Liver Disease (CLD)
by: Harshavardhan Rao B, et al.
Published: (2021-01-01)

Emergent Biomarkers of Residual Cardiovascular Risk in Patients with Low HDL-c and/or High Triglycerides and Average LDL-c Concentrations: Focus on HDL Subpopulations, Oxidized LDL, Adiponectin, and Uric Acid
by: Filipa Mascarenhas-Melo, et al.
Published: (2013-01-01)

Cholesterol, triglycerides, HDL, and nitric oxide as determinants of resting heart rate variability in non-hospitalized mild post-COVID individuals: a cross-sectional study
by: Lucivalda Viegas de Almeida, et al.
Published: (2025-01-01)

Rosuvastatin effects on the HDL proteome in hyperlipidemic patients
by: Vavlukis Ana, et al.
Published: (2023-09-01)

Increased pro-SFTPB in HDL promotes the pro-inflammatory transition of HDL and represents a sign of poor prognosis in ARDS patients
by: Liu Yang, et al.
Published: (2025-01-01)

PPIH is a novel diagnostic biomarker associated with immune infiltration in cholangiocarcinoma
by: Jun Ye, et al.
Published: (2025-02-01)

Glucometabolic-Related Genes as Diagnostic Biomarkers and Therapeutic Targets for Alzheimer’s Disease and Type 2 Diabetes Mellitus: A Bioinformatics Analysis
by: Shuo Liu, et al.
Published: (2024-01-01)

Serum Concentrations of Betatrophin and Its Association with Indirect Indices of Insulin Resistance and Beta Cell Function in Women with Polycystic Ovary Syndrome
by: Agnieszka Adamska, et al.
Published: (2017-01-01)

HDL Subclass Distribution Shifts with Increasing Central Adiposity
by: Nicholas J. Woudberg, et al.
Published: (2019-01-01)

Age- and Gender-Related Differences in LDL-Cholesterol Management in Outpatients with Type 2 Diabetes Mellitus
by: Giuseppina Russo, et al.
Published: (2015-01-01)

Evaluation of low cryptococcal antigen titer as determined by the lateral flow assay in serum and cerebrospinal fluid among HIV-negative patients: a retrospective diagnostic accuracy study
by: Xuan Wang, et al.
Published: (2020-03-01)

Reverse Cholesterol Transport Pathway and Cholesterol Efflux in Diabetic Retinopathy
by: Xinyuan Zhang, et al.
Published: (2021-01-01)

Association of LDL‐C/HDL‐C Ratio With Hyperuricemia: A National Cohort Study
by: Yanyu Zhang, et al.
Published: (2025-01-01)

HDL proteome and apolipoproteins concentrations in severe ICU COVID-19 patients
by: Floran Begue, et al.
Published: (2025-01-01)

Layered Babinet complementary patterns acting as asymmetric negative index metamaterial
by: Emese Tóth, et al.
Published: (2024-11-01)

Beyond LDL cholesterol: remnant cholesterol is associated with cardiometabolic risk factors in children
by: Ana Torres-Costoso, et al.
Published: (2025-01-01)

Dual Inhibition of CDK4/6 and CDK7 Suppresses Triple‐Negative Breast Cancer Progression via Epigenetic Modulation of SREBP1‐Regulated Cholesterol Metabolism
by: Yilan Yang, et al.
Published: (2025-02-01)

Serum HDL and their subfractions are impaired in multisystem inflammatory syndrome in children (MIS-C)
by: Antonietta Giannattasio, et al.
Published: (2025-01-01)

Can the monocyte/HDL ratio predict ear effusion in adenoid vegetation patients?
by: Elif Kaya Çelik, et al.
Published: (2025-01-01)

A novel index for diagnosis of type 2 diabetes mellitus: Cholesterol, High density lipoprotein, and Glucose (CHG) index
by: Amin Mansoori, et al.
Published: (2025-02-01)

YAP1 as a Novel Negative Biomarker of Immune Checkpoint Inhibitors for EGFR-Mutant Non-Small-Cell Lung Cancer
by: Ling-Chen Li, et al.
Published: (2023-01-01)

Urinary NGAL and RBP Are Biomarkers of Normoalbuminuric Renal Insufficiency in Type 2 Diabetes Mellitus
by: Aimei Li, et al.
Published: (2019-01-01)

Urinary Exosomal Long Noncoding RNA TERC as a Noninvasive Diagnostic and Prognostic Biomarker for Bladder Urothelial Carcinoma
by: Chen Chen, et al.
Published: (2022-01-01)

High HDL-C and high LDL-C are risk factors of pterygium in a population-based cross-sectional study in Southern China: the Dongguan Eye Study
by: Liang Zhang, et al.
Published: (2022-06-01)

Novel loci for triglyceride/HDL-C ratio longitudinal change among subjects without T2D
by: Lihua Wang, et al.
Published: (2025-01-01)

Frameshift variation in the HMG-CoA reductase gene and unresponsiveness to cholesterol-lowering drugs in type 2 diabetes mellitus patients
by: Esmat Khaleqsefat, et al.
Published: (2025-01-01)

NET-Related Gene as Potential Diagnostic Biomarkers for Diabetic Tubulointerstitial Injury
by: Yufeng Liang, et al.
Published: (2024-01-01)

Relationship between uric acid to HDL ratio and extent and severity of coronary artery disease
by: Mehmet Yaman, et al.
Published: (2024-11-01)

The association of visceral and subcutaneous fat areas with phenotypic age in non-elderly adults, mediated by HOMA-IR and HDL-C
by: Yuanhong Liu, et al.
Published: (2025-01-01)

Identifying plasma exosome antigens as a potential diagnostic biomarker for tuberculosis disease
by: Yan Jiang, et al.
Published: (2025-01-01)

U-shaped association between TC/HDL-C ratio and osteoporosis risk in older adults
by: Chuanwei Zhao, et al.
Published: (2025-02-01)

HDL Particle Size and Functionality Comparison between Patients with and without Confirmed Acute Myocardial Infarction
by: Raissa de Miranda Teixeira, et al.
Published: (2019-01-01)