Drug‐Induced Cauda Equina Syndrome in an 8‐Year‐Old Boy With Acute Lymphoblastic Leukemia: An Uncommon Case Report
ABSTRACT Intrathecal methotrexate can cause cauda equina syndrome in pediatric ALL patients, as demonstrated in this rare case of an 8‐year‐old boy. Symptoms included progressive limb weakness and urinary retention. Early recognition, prompt discontinuation of the offending agent, and multidisciplin...
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| Format: | Article |
| Language: | English |
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Wiley
2025-01-01
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| Series: | Clinical Case Reports |
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| Online Access: | https://doi.org/10.1002/ccr3.70122 |
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| author | Marzieh Babaee Mohsen Javadzadeh Ali Hazeghi |
| author_facet | Marzieh Babaee Mohsen Javadzadeh Ali Hazeghi |
| author_sort | Marzieh Babaee |
| collection | DOAJ |
| description | ABSTRACT Intrathecal methotrexate can cause cauda equina syndrome in pediatric ALL patients, as demonstrated in this rare case of an 8‐year‐old boy. Symptoms included progressive limb weakness and urinary retention. Early recognition, prompt discontinuation of the offending agent, and multidisciplinary management are crucial. Vigilant neurological monitoring is essential for pediatric acute lymphoblastic leukemia patients receiving intrathecal chemotherapy. |
| format | Article |
| id | doaj-art-f84898fd234748d9a6365424bcf24e57 |
| institution | Kabale University |
| issn | 2050-0904 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical Case Reports |
| spelling | doaj-art-f84898fd234748d9a6365424bcf24e572025-01-24T05:08:46ZengWileyClinical Case Reports2050-09042025-01-01131n/an/a10.1002/ccr3.70122Drug‐Induced Cauda Equina Syndrome in an 8‐Year‐Old Boy With Acute Lymphoblastic Leukemia: An Uncommon Case ReportMarzieh Babaee0Mohsen Javadzadeh1Ali Hazeghi2Physical Medicine and Rehabilitation Research Center Shahid Beheshti University of Medical Sciences Tehran IranPediatric Neurology Department, Pediatric Neurology Research Center Shahid Beheshti University of Medical Sciences Tehran IranPediatric Neurology Department, Pediatric Neurology Research Center Shahid Beheshti University of Medical Sciences Tehran IranABSTRACT Intrathecal methotrexate can cause cauda equina syndrome in pediatric ALL patients, as demonstrated in this rare case of an 8‐year‐old boy. Symptoms included progressive limb weakness and urinary retention. Early recognition, prompt discontinuation of the offending agent, and multidisciplinary management are crucial. Vigilant neurological monitoring is essential for pediatric acute lymphoblastic leukemia patients receiving intrathecal chemotherapy.https://doi.org/10.1002/ccr3.70122cauda equina syndromemethotrexatepediatricsprecursor cell lymphoblastic leukemia‐lymphoma |
| spellingShingle | Marzieh Babaee Mohsen Javadzadeh Ali Hazeghi Drug‐Induced Cauda Equina Syndrome in an 8‐Year‐Old Boy With Acute Lymphoblastic Leukemia: An Uncommon Case Report Clinical Case Reports cauda equina syndrome methotrexate pediatrics precursor cell lymphoblastic leukemia‐lymphoma |
| title | Drug‐Induced Cauda Equina Syndrome in an 8‐Year‐Old Boy With Acute Lymphoblastic Leukemia: An Uncommon Case Report |
| title_full | Drug‐Induced Cauda Equina Syndrome in an 8‐Year‐Old Boy With Acute Lymphoblastic Leukemia: An Uncommon Case Report |
| title_fullStr | Drug‐Induced Cauda Equina Syndrome in an 8‐Year‐Old Boy With Acute Lymphoblastic Leukemia: An Uncommon Case Report |
| title_full_unstemmed | Drug‐Induced Cauda Equina Syndrome in an 8‐Year‐Old Boy With Acute Lymphoblastic Leukemia: An Uncommon Case Report |
| title_short | Drug‐Induced Cauda Equina Syndrome in an 8‐Year‐Old Boy With Acute Lymphoblastic Leukemia: An Uncommon Case Report |
| title_sort | drug induced cauda equina syndrome in an 8 year old boy with acute lymphoblastic leukemia an uncommon case report |
| topic | cauda equina syndrome methotrexate pediatrics precursor cell lymphoblastic leukemia‐lymphoma |
| url | https://doi.org/10.1002/ccr3.70122 |
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