Neurophysiological gradient in the Parkinsonian subthalamic nucleus as a marker for motor symptoms and apathy

Neurophysiological gradient in the Parkinsonian subthalamic nucleus as a marker for motor symptoms and apathy

Abstract Sensing-based deep brain stimulation should optimally consider both the motor and neuropsychiatric domain to maximize quality of life of Parkinson’s disease (PD) patients. Here we characterize the neurophysiological properties of the subthalamic nucleus (STN) in 69 PD patients using a newly...

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Main Authors: Elena Bernasconi, Deborah Amstutz, Alberto Averna, Petra Fischer, Mario Sousa, Ines Debove, Katrin Petermann, Laura Alva, Andreia D. Magalhães, M. Lenard Lachenmayer, Thuy-Anh K. Nguyen, Michael Schuepbach, Andreas Nowacki, Claudio Pollo, Paul Krack, Gerd Tinkhauser
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-024-00848-2
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https://doi.org/10.1038/s41531-024-00848-2

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