Strategies Aimed at Nox4 Oxidase Inhibition Employing Peptides from Nox4 B-Loop and C-Terminus and p22phox N-Terminus: An Elusive Target

Although NADPH oxidase 4 (Nox4) is the most abundant Nox isoform in systemic vascular endothelial and smooth muscle cells, its function in the vascular tissue is not entirely known. The literature describes a pathophysiological role for Nox4 in cardiovascular disease; however, some studies have repo...

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Bibliographic Details
Main Authors: Gábor Csányi, Patrick J. Pagano
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:International Journal of Hypertension
Online Access:http://dx.doi.org/10.1155/2013/842827
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