TOP2A modulates signaling via the AKT/mTOR pathway to promote ovarian cancer cell proliferation

TOP2A modulates signaling via the AKT/mTOR pathway to promote ovarian cancer cell proliferation

Ovarian cancer (OC) is a form of gynecological malignancy that is associated with worse patient outcomes than any other cancer of the female reproductive tract. Topoisomerase II α (TOP2A) is commonly regarded as an oncogene that is associated with malignant disease progression in a variety of cancer...

Full description

Saved in:
Bibliographic Details
Main Authors: Kaiwen Zhang, Xingyu Zheng, Yiqing Sun, Xinyu Feng, Xirong Wu, Wenlu Liu, Chao Gao, Ye Yan, Wenyan Tian, Yingmei Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Cancer Biology & Therapy
Subjects:
Ovarian cancer
TOP2A
prognosis
proliferation
rescue experiments
AKT/mTOR signaling pathway
Online Access:https://www.tandfonline.com/doi/10.1080/15384047.2024.2325126
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.tandfonline.com/doi/10.1080/15384047.2024.2325126

Similar Items