The solvent effect, preferential solvation of metformin hydrochloride in binary mixed solvents of methanol/ethanol + water mixtures from 278.15 K to 323.15 K
This study provides a novel quantitative analysis of metformin hydrochloride (MET-HCl) solvation behavior in binary solvents mixtures of methyl alcohol and water, as well as ethyl alcohol and water, addressing critical gaps in understanding its solubility mechanisms for pharmaceutical formulation. W...
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Main Authors: | Adel Noubigh, Abdalazeem A. Omar, Manef Abderrabba |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2025-04-01
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Series: | South African Journal of Chemical Engineering |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1026918525000071 |
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