The solvent effect, preferential solvation of metformin hydrochloride in binary mixed solvents of methanol/ethanol + water mixtures from 278.15 K to 323.15 K

This study provides a novel quantitative analysis of metformin hydrochloride (MET-HCl) solvation behavior in binary solvents mixtures of methyl alcohol and water, as well as ethyl alcohol and water, addressing critical gaps in understanding its solubility mechanisms for pharmaceutical formulation. W...

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Bibliographic Details
Main Authors: Adel Noubigh, Abdalazeem A. Omar, Manef Abderrabba
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:South African Journal of Chemical Engineering
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1026918525000071
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