Management of Early Stage, High-Risk Endometrial Carcinoma: Preoperative and Surgical Considerations

Endometrial cancer is the most common gynecologic malignancy in the developed world. Most cases are diagnosed at an early stage and have low-grade histology, portending an overall excellent prognosis. There exists a subgroup of patients with early, high-risk disease, whose management remains contr...

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Main Authors: Sareena Singh, Shandhini Raidoo, Gaetan Pettigrew, Robert DeBernardo
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Obstetrics and Gynecology International
Online Access:http://dx.doi.org/10.1155/2013/757249
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author Sareena Singh
Shandhini Raidoo
Gaetan Pettigrew
Robert DeBernardo
author_facet Sareena Singh
Shandhini Raidoo
Gaetan Pettigrew
Robert DeBernardo
author_sort Sareena Singh
collection DOAJ
description Endometrial cancer is the most common gynecologic malignancy in the developed world. Most cases are diagnosed at an early stage and have low-grade histology, portending an overall excellent prognosis. There exists a subgroup of patients with early, high-risk disease, whose management remains controversial, as current data is clouded by inclusion of early stage tumors with different high-risk features for recurrence, unstandardized protocols for surgical staging, and an evolving staging system by which we are grouping these patients. Here, we present preoperative and intraoperative considerations that should be taken into account when planning surgical management for this population of patients.
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institution Kabale University
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series Obstetrics and Gynecology International
spelling doaj-art-f7fd610fcc4641629ae67e4be3cf4c9d2025-02-03T06:01:42ZengWileyObstetrics and Gynecology International1687-95891687-95972013-01-01201310.1155/2013/757249757249Management of Early Stage, High-Risk Endometrial Carcinoma: Preoperative and Surgical ConsiderationsSareena Singh0Shandhini Raidoo1Gaetan Pettigrew2Robert DeBernardo3Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University Hospitals Case Medical Center, Cleveland, OH 44106, USADivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, University Hospitals Case Medical Center, Cleveland, OH 44106, USADivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, University Hospitals Case Medical Center, Cleveland, OH 44106, USADivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, University Hospitals Case Medical Center, Cleveland, OH 44106, USAEndometrial cancer is the most common gynecologic malignancy in the developed world. Most cases are diagnosed at an early stage and have low-grade histology, portending an overall excellent prognosis. There exists a subgroup of patients with early, high-risk disease, whose management remains controversial, as current data is clouded by inclusion of early stage tumors with different high-risk features for recurrence, unstandardized protocols for surgical staging, and an evolving staging system by which we are grouping these patients. Here, we present preoperative and intraoperative considerations that should be taken into account when planning surgical management for this population of patients.http://dx.doi.org/10.1155/2013/757249
spellingShingle Sareena Singh
Shandhini Raidoo
Gaetan Pettigrew
Robert DeBernardo
Management of Early Stage, High-Risk Endometrial Carcinoma: Preoperative and Surgical Considerations
Obstetrics and Gynecology International
title Management of Early Stage, High-Risk Endometrial Carcinoma: Preoperative and Surgical Considerations
title_full Management of Early Stage, High-Risk Endometrial Carcinoma: Preoperative and Surgical Considerations
title_fullStr Management of Early Stage, High-Risk Endometrial Carcinoma: Preoperative and Surgical Considerations
title_full_unstemmed Management of Early Stage, High-Risk Endometrial Carcinoma: Preoperative and Surgical Considerations
title_short Management of Early Stage, High-Risk Endometrial Carcinoma: Preoperative and Surgical Considerations
title_sort management of early stage high risk endometrial carcinoma preoperative and surgical considerations
url http://dx.doi.org/10.1155/2013/757249
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