Characterization of Coelenterazine Analogs for Measurements of Luciferase Activity in Live Cells and Living Animals

In vivo imaging of bioluminescent reporters relies on expression of light-emitting enzymes, luciferases, and delivery of chemical substrates to expressing cells. Coelenterazine (CLZN) is the substrate for a group of bioluminescent enzymes obtained from marine organisms. At present, there are more th...

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Bibliographic Details
Main Authors: Hui Zhao, Timothy C. Doyle, Ronald J. Wong, Yuan Cao, David K. Stevenson, David Piwnica-Worms, Christopher H. Contag
Format: Article
Language:English
Published: SAGE Publishing 2004-01-01
Series:Molecular Imaging
Online Access:https://doi.org/10.1162/15353500200403181
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