Submassive Pulmonary Thromboembolism in a Patient with Thrombocytopenia: Therapeutic Challenge

Venous thromboembolic disease is an important cause of mortality worldwide. A widely recognized risk factor is active neoplasia, mainly hematological tumors, in which associated thrombocytopenia can be a frequent complication. We present the case of a patient with submassive pulmonary thromboembolis...

Full description

Saved in:
Bibliographic Details
Main Authors: Ronni Andrea Muñoz Tovar, Luis Carlos Alvarez Perdomo, Sandra Milena Rojas Molina, Silvana Jimenez Salazar
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Case Reports in Critical Care
Online Access:http://dx.doi.org/10.1155/2019/1919401
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832549623801053184
author Ronni Andrea Muñoz Tovar
Luis Carlos Alvarez Perdomo
Sandra Milena Rojas Molina
Silvana Jimenez Salazar
author_facet Ronni Andrea Muñoz Tovar
Luis Carlos Alvarez Perdomo
Sandra Milena Rojas Molina
Silvana Jimenez Salazar
author_sort Ronni Andrea Muñoz Tovar
collection DOAJ
description Venous thromboembolic disease is an important cause of mortality worldwide. A widely recognized risk factor is active neoplasia, mainly hematological tumors, in which associated thrombocytopenia can be a frequent complication. We present the case of a patient with submassive pulmonary thromboembolism associated with severe thrombocytopenia with signs of right heart failure and a requirement for systemic thrombolysis and anticoagulation, however with absolute contraindication for them. The case establishes a therapeutic challenge for the treating group, leading us to carry out an extensive search of the literature and propose a management algorithm in this complex situation.
format Article
id doaj-art-f7bfaf6c6cc94ad4a51e2b4770d74f50
institution Kabale University
issn 2090-6420
2090-6439
language English
publishDate 2019-01-01
publisher Wiley
record_format Article
series Case Reports in Critical Care
spelling doaj-art-f7bfaf6c6cc94ad4a51e2b4770d74f502025-02-03T06:10:53ZengWileyCase Reports in Critical Care2090-64202090-64392019-01-01201910.1155/2019/19194011919401Submassive Pulmonary Thromboembolism in a Patient with Thrombocytopenia: Therapeutic ChallengeRonni Andrea Muñoz Tovar0Luis Carlos Alvarez Perdomo1Sandra Milena Rojas Molina2Silvana Jimenez Salazar3Critical Care, Hospital Universitario Hernando Moncaleano Perdomo, Neiva, Huila, ColombiaInternal Medicine, Hospital Universitario Hernando Moncaleano Perdomo, Neiva, Huila, ColombiaEpidemiology, Surgery, Universidad Surcolombiana, Neiva Huila, ColombiaInternal Medicine, Universidad Surcolombiana, Neiva Huila, ColombiaVenous thromboembolic disease is an important cause of mortality worldwide. A widely recognized risk factor is active neoplasia, mainly hematological tumors, in which associated thrombocytopenia can be a frequent complication. We present the case of a patient with submassive pulmonary thromboembolism associated with severe thrombocytopenia with signs of right heart failure and a requirement for systemic thrombolysis and anticoagulation, however with absolute contraindication for them. The case establishes a therapeutic challenge for the treating group, leading us to carry out an extensive search of the literature and propose a management algorithm in this complex situation.http://dx.doi.org/10.1155/2019/1919401
spellingShingle Ronni Andrea Muñoz Tovar
Luis Carlos Alvarez Perdomo
Sandra Milena Rojas Molina
Silvana Jimenez Salazar
Submassive Pulmonary Thromboembolism in a Patient with Thrombocytopenia: Therapeutic Challenge
Case Reports in Critical Care
title Submassive Pulmonary Thromboembolism in a Patient with Thrombocytopenia: Therapeutic Challenge
title_full Submassive Pulmonary Thromboembolism in a Patient with Thrombocytopenia: Therapeutic Challenge
title_fullStr Submassive Pulmonary Thromboembolism in a Patient with Thrombocytopenia: Therapeutic Challenge
title_full_unstemmed Submassive Pulmonary Thromboembolism in a Patient with Thrombocytopenia: Therapeutic Challenge
title_short Submassive Pulmonary Thromboembolism in a Patient with Thrombocytopenia: Therapeutic Challenge
title_sort submassive pulmonary thromboembolism in a patient with thrombocytopenia therapeutic challenge
url http://dx.doi.org/10.1155/2019/1919401
work_keys_str_mv AT ronniandreamunoztovar submassivepulmonarythromboembolisminapatientwiththrombocytopeniatherapeuticchallenge
AT luiscarlosalvarezperdomo submassivepulmonarythromboembolisminapatientwiththrombocytopeniatherapeuticchallenge
AT sandramilenarojasmolina submassivepulmonarythromboembolisminapatientwiththrombocytopeniatherapeuticchallenge
AT silvanajimenezsalazar submassivepulmonarythromboembolisminapatientwiththrombocytopeniatherapeuticchallenge