Depth-dependent PD-L1 sampling of head and neck squamous cell carcinoma (HNSCC) – implications for PD-1/PD-L1 checkpoint inhibitor immunotherapy

Depth-dependent PD-L1 sampling of head and neck squamous cell carcinoma (HNSCC) – implications for PD-1/PD-L1 checkpoint inhibitor immunotherapy

At present, PD-L1 scoring is the gold standard in evaluating a cancer patient's suitability for receiving PD-1/PD-L1 checkpoint inhibitor immunotherapy (CIT). Either tumor proportion score (TPS) or combined positive score (CPS) can be used to select head and neck squamous cell carcinoma (HNSCC)...

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Bibliographic Details
Main Authors: Madhusudan Roy, Jing-Tang Lin, Sohidul Mondal, Mei-Chun Lin, Chih-Yu Leu, Yen-Lin Huang, Chen-Yuan Dong, Pei-Jen Lou
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Oral Oncology Reports
Subjects:
Head and neck squamous cell carcinoma (HNSCC)
Immunotherapy
PD-L1 labeling
Tumor proportion score (TPS)
Combined positive score (CPS)
Online Access:http://www.sciencedirect.com/science/article/pii/S2772906024000347
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