The Influence of Juvenile Graves’ Ophthalmopathy on Graves’ Disease Course
Purpose. To investigate juvenile Graves’ ophthalmopathy (GO) signs and compare Graves’ disease (GD) course in patients with or without GO. Patients and Methods. There were analyzed data (visual acuity, proptosis, palpebral fissure measurements, clinical activity score (CAS), and the course of GD) of...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2017/4853905 |
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| author | Jurate Jankauskiene Dalia Jarusaitiene |
| author_facet | Jurate Jankauskiene Dalia Jarusaitiene |
| author_sort | Jurate Jankauskiene |
| collection | DOAJ |
| description | Purpose. To investigate juvenile Graves’ ophthalmopathy (GO) signs and compare Graves’ disease (GD) course in patients with or without GO. Patients and Methods. There were analyzed data (visual acuity, proptosis, palpebral fissure measurements, clinical activity score (CAS), and the course of GD) of 67 children who have been newly diagnosed with GD. 26.9% of patients with GD had signs of ophthalmopathy (GO+), and 73.1% were without ophthalmopathy (GO−). Results. Upper eyelid retraction (72.3%), proptosis (66.7%), and soft tissue changes (27.8−38.9%) were in GO+ patients. The palpebral fissure, CAS, and proptosis values were greater in the GO+ group than in the GO− group (p<0.001). GD course in GO+ patients was longer than that in GO− patients (p<0.001). The duration of the first remission was longer in GO− than in GO+ patients (p<0.001). The duration of first remission was longer than one year for 61.2% in GO− and 33.3% in GO+ patients (p<0.02). Conclusion. The common manifestations of juvenile GO patients were upper eyelid retraction, proptosis, and soft tissue involvement. The study demonstrates that pediatric patients with GO are more likely to have a severe course of autoimmune thyroid disease. |
| format | Article |
| id | doaj-art-f721a2ef512345ccb9362472c8c804ce |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-f721a2ef512345ccb9362472c8c804ce2025-02-03T00:59:05ZengWileyJournal of Ophthalmology2090-004X2090-00582017-01-01201710.1155/2017/48539054853905The Influence of Juvenile Graves’ Ophthalmopathy on Graves’ Disease CourseJurate Jankauskiene0Dalia Jarusaitiene1Eye Clinic of Lithuanian University of Health Sciences, Kaunas, LithuaniaEye Clinic of Lithuanian University of Health Sciences, Kaunas, LithuaniaPurpose. To investigate juvenile Graves’ ophthalmopathy (GO) signs and compare Graves’ disease (GD) course in patients with or without GO. Patients and Methods. There were analyzed data (visual acuity, proptosis, palpebral fissure measurements, clinical activity score (CAS), and the course of GD) of 67 children who have been newly diagnosed with GD. 26.9% of patients with GD had signs of ophthalmopathy (GO+), and 73.1% were without ophthalmopathy (GO−). Results. Upper eyelid retraction (72.3%), proptosis (66.7%), and soft tissue changes (27.8−38.9%) were in GO+ patients. The palpebral fissure, CAS, and proptosis values were greater in the GO+ group than in the GO− group (p<0.001). GD course in GO+ patients was longer than that in GO− patients (p<0.001). The duration of the first remission was longer in GO− than in GO+ patients (p<0.001). The duration of first remission was longer than one year for 61.2% in GO− and 33.3% in GO+ patients (p<0.02). Conclusion. The common manifestations of juvenile GO patients were upper eyelid retraction, proptosis, and soft tissue involvement. The study demonstrates that pediatric patients with GO are more likely to have a severe course of autoimmune thyroid disease.http://dx.doi.org/10.1155/2017/4853905 |
| spellingShingle | Jurate Jankauskiene Dalia Jarusaitiene The Influence of Juvenile Graves’ Ophthalmopathy on Graves’ Disease Course Journal of Ophthalmology |
| title | The Influence of Juvenile Graves’ Ophthalmopathy on Graves’ Disease Course |
| title_full | The Influence of Juvenile Graves’ Ophthalmopathy on Graves’ Disease Course |
| title_fullStr | The Influence of Juvenile Graves’ Ophthalmopathy on Graves’ Disease Course |
| title_full_unstemmed | The Influence of Juvenile Graves’ Ophthalmopathy on Graves’ Disease Course |
| title_short | The Influence of Juvenile Graves’ Ophthalmopathy on Graves’ Disease Course |
| title_sort | influence of juvenile graves ophthalmopathy on graves disease course |
| url | http://dx.doi.org/10.1155/2017/4853905 |
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